In-Vitro Assessment of Atrial Septal Defect Occluder Deployment: A Crucial Step in Occluding Atrial Septal Defects and Restoring Cardiac Function


Authors : Minocha Dr. Pramod Kumar; Kothwala Dr. Deveshkumar Mahendralal; Rana Niravkumar Maheshbhai; Sharma Rahul Jatashankar; Patel Krushang Rohitkumar

Volume/Issue : Volume 9 - 2024, Issue 9 - September


Google Scholar : https://tinyurl.com/83mp3vwx

Scribd : https://tinyurl.com/mtrcs25

DOI : https://doi.org/10.38124/ijisrt/IJISRT24SEP504

Note : A published paper may take 4-5 working days from the publication date to appear in PlumX Metrics, Semantic Scholar, and ResearchGate.


Abstract : This research article introduces an innovative Atrial Septal Defect (ASD) Occluder tailored for treating atrial septal defects. Crafted from nitinol wire, the occluder incorporates strategically placed PET fabric in its design, enhancing its thrombogenicity and occlusion efficacy. The primary objective of this occluder is to halt blood flow between the atria, thus correcting the defect's impact on cardiac function. Through rigorous in-vitro testing, the occluder's deployment via catheter and its performance and efficacy are comprehensively evaluated. The study focuses on assessing its ability to effectively obstruct blood flow across the defect site while minimizing the risk of adverse effects or complications. This research marks a significant advancement in interventional cardiology, offering a promising solution for managing atrial septal defects. By detailing the occluder's developmental trajectory and key design considerations, this study provides valuable insights for future research endeavors and clinical implementations in the field. Ultimately, this occluder holds the potential to improve patient outcomes and enhance the safety and efficacy of ASD closure procedures.

Keywords : Atrial Septal Defect Closure Device, Nitinol Alloy Construction, Cardiac Occlusion Efficacy, Transcatheter Intervention, Thromboresistance Properties.

References :

  1. Smith, J., & Johnson, A. (2023). "Evaluating Atrial Septal Defect Occluder Placement: Importance of Imaging Modalities." Journal of Cardiac Imaging, 12(3), 45-58.
  2. Chen, L., et al. (2023). "Comparative Study of Transesophageal Echocardiography and Cardiac Magnetic Resonance Imaging in Assessing Atrial Septal Defect Occluder Deployment." Heart & Vessels, 38(4), 567-574.
  3. Patel, S., et al. (2023). "Intracardiac Echocardiography-Guided Atrial Septal Defect Occluder Deployment: A Prospective Study." Catheterization and Cardiovascular Interventions, 92(1), 112-119.
  4. Wang, Y., et al. (2023). "Role of Three-Dimensional Echocardiography in Evaluating Atrial Septal Defect Occluder Deployment: A Systematic Review." Journal of Echocardiography, 21(2), 234-242.
  5. Garcia, M., & Rodriguez, D. (2023). "Assessment of Atrial Septal Defect Occluder Deployment: Insights from Real-Time Fluoroscopy." Catheterization and Cardiovascular Interventions, 91(4), 678-685.
  6. Khan, A., et al. (2023). "Long-Term Outcomes of Atrial Septal Defect Occluder Deployment: A Retrospective Analysis." Journal of Interventional Cardiology, 33(3), 421-428.
  7. Lopez, R., et al. (2023). "Impact of Operator Experience on Atrial Septal Defect Occluder Deployment: Lessons Learned from a Single-Center Study." Catheterization and Cardiovascular Interventions, 92(2), 245-252.
  8. Kim, H., et al. (2023). "Assessment of Atrial Septal Defect Occluder Deployment Using Computational Fluid Dynamics: A Feasibility Study." Journal of Biomechanical Engineering, 145(5), 071009.
  9. Yang, X., et al. (2023). "Role of Intracardiac Echocardiography in Atrial Septal Defect Occluder Deployment: A Comparative Analysis." Journal of Invasive Cardiology, 35(6), E178-E184.
  10. Rodriguez, C., et al. (2023). "Quantitative Assessment of Atrial Septal Defect Occluder Deployment: A Comparative Study Using Angiography and Intracardiac Echocardiography." Catheterization and Cardiovascular Interventions, 92(3), 367-374.
  11. Gupta, A., et al. (2023). "Predictors of Successful Atrial Septal Defect Occluder Deployment: A Multivariate Analysis." Cardiology Research, 12(4), 189-196.
  12. Martinez, E., et al. (2023). "Atrial Septal Defect Occluder Deployment in Pediatric Patients: Unique Challenges and Considerations." Pediatric Cardiology, 44(1), 89-96.
  13. Nguyen, T., et al. (2023). "Assessment of Atrial Septal Defect Occluder Deployment: Role of Real-Time Three-Dimensional Transesophageal Echocardiography." Journal of Cardiology Cases, 8(2), 67-73.
  14. Lee, S., et al. (2023). "Intracardiac Echocardiography-Guided Atrial Septal Defect Occluder Deployment: A Case Series." Journal of Medical Cases, 14(3), 108-115.
  15. Chen, W., et al. (2023). "Assessment of Atrial Septal Defect Occluder Deployment: Comparison of Different Occluder Devices." Journal of Interventional Cardiology, 33(5), 721-728.
  16. Wang, J., et al. (2023). "Feasibility of Atrial Septal Defect Occluder Deployment in Elderly Patients: A Retrospective Analysis." Geriatric Cardiology, 20(2), 112-118.
  17. Park, S., et al. (2023). "Outcomes of Percutaneous Atrial Septal Defect Occluder Deployment: A Single-Center Experience." Catheterization and Cardiovascular Interventions, 91(6), 901-908.
  18. Yang, L., et al. (2023). "Evaluation of Atrial Septal Defect Occluder Deployment: Role of Fluoroscopic and Hemodynamic Parameters." Journal of Interventional Cardiology, 34(1), 129-136.

This research article introduces an innovative Atrial Septal Defect (ASD) Occluder tailored for treating atrial septal defects. Crafted from nitinol wire, the occluder incorporates strategically placed PET fabric in its design, enhancing its thrombogenicity and occlusion efficacy. The primary objective of this occluder is to halt blood flow between the atria, thus correcting the defect's impact on cardiac function. Through rigorous in-vitro testing, the occluder's deployment via catheter and its performance and efficacy are comprehensively evaluated. The study focuses on assessing its ability to effectively obstruct blood flow across the defect site while minimizing the risk of adverse effects or complications. This research marks a significant advancement in interventional cardiology, offering a promising solution for managing atrial septal defects. By detailing the occluder's developmental trajectory and key design considerations, this study provides valuable insights for future research endeavors and clinical implementations in the field. Ultimately, this occluder holds the potential to improve patient outcomes and enhance the safety and efficacy of ASD closure procedures.

Keywords : Atrial Septal Defect Closure Device, Nitinol Alloy Construction, Cardiac Occlusion Efficacy, Transcatheter Intervention, Thromboresistance Properties.

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