Authors :
Dr. Muhammad Shakeel; Dr. Muhammad Bilal; Dr. Abdullah Jan; Dr. Adnan Khan; Dr. Ubaid Ullah; Dr. Saddam Hussain; Dr. Annas Sani; Dr. Tayyab Mustajab Khan
Volume/Issue :
Volume 8 - 2023, Issue 10 - October
Google Scholar :
https://tinyurl.com/awpanwpu
Scribd :
https://tinyurl.com/3v3akkzt
DOI :
https://doi.org/10.5281/zenodo.10487788
Abstract :
Background: This study compared the effectiveness of
two therapy techniques for treating a certain medical
condition: intra-articular steroid injection (Group A)
and platelet rich plasma injection (Group B). The medial
femorotibial compartment, for instance, frequently
exhibits the highest decrease of joint space in the
osteoarthritic knee. Treatment for osteoarthritis aims to
reduce discomfort and enhance functional status.
Medium-term improvements are seen with intra-
articular platelet-rich plasma, balneotherapy, and
whole-body vibration. The study is intended to
demonstrate knee osteoarthritis and establish
appropriate treatment guidelines. to determine the mean
VAS score in individuals with knee osteoarthritis after
intra-articular PRP or steroid injection and to evaluate
which treatment is more effective at reducing pain for
patients with osteoarthritis of the knee: PRP or steroid
injections.
Methodology: Department of Orthopedics Surgery &
Trauma, lady reading hospital peshawer, UPON
ETHICAL Comitte Approval. Thirty patients with knee
osteoarthritis were studied in each group from 1 JAN
2022 to 31 December 2022. PRP and steroid groups of
patients were randomly assigned using randomization
through non-probability consecutive sampling. SPSS-24
Version was used to recode and analyze the results of the
CONTROL TRIAL. The male-to-female ratio, age
distribution, and pain outcomes both before and after
treatment were also examined in the study. The male-to-
female ratio in Group A was 1:3, whereas the ratio in
Group B was 1:3.75. Both therapies were used, and their
effects in reducing pain were evaluated. The results
showed that both groups had a larger proportion of
females. The groups' age distributions varied, but there
were no statistically significant differences between
them.
Results: The study consisted of 60 patients in total. They
were evenly divided between the two groups. Patients in
group A had a mean age of 59.93 years plus 7.48
standard deviations, whereas those in group B had a
mean age of 61.68 years plus 7.22 SD. After treatment,
when pain levels were compared, Group A reported
4.7+1.31SD of pain, whereas Group B reported
6.03+1.18SD of pain. This difference was statistically
significant using an independent t-test, with a p-value of
0.000. Pre-treatment pain levels between Group A
(mean: 7.93) and Group B (mean: 8.03) were
comparable, and there was little change after therapy. In
contrast, Group A showed a statistically significant
reduction in pain following therapy (mean: 4.7) as
compared to Group B (mean: 6.03).
Conclusion: This study highlights the potential
advantages of intra-articular steroid injections versus
platelet rich plasma injections for the treatment of pain.
Keywords :
Knee Osteoarthritis, Steroid, Platelet Rich Plasma.
Background: This study compared the effectiveness of
two therapy techniques for treating a certain medical
condition: intra-articular steroid injection (Group A)
and platelet rich plasma injection (Group B). The medial
femorotibial compartment, for instance, frequently
exhibits the highest decrease of joint space in the
osteoarthritic knee. Treatment for osteoarthritis aims to
reduce discomfort and enhance functional status.
Medium-term improvements are seen with intra-
articular platelet-rich plasma, balneotherapy, and
whole-body vibration. The study is intended to
demonstrate knee osteoarthritis and establish
appropriate treatment guidelines. to determine the mean
VAS score in individuals with knee osteoarthritis after
intra-articular PRP or steroid injection and to evaluate
which treatment is more effective at reducing pain for
patients with osteoarthritis of the knee: PRP or steroid
injections.
Methodology: Department of Orthopedics Surgery &
Trauma, lady reading hospital peshawer, UPON
ETHICAL Comitte Approval. Thirty patients with knee
osteoarthritis were studied in each group from 1 JAN
2022 to 31 December 2022. PRP and steroid groups of
patients were randomly assigned using randomization
through non-probability consecutive sampling. SPSS-24
Version was used to recode and analyze the results of the
CONTROL TRIAL. The male-to-female ratio, age
distribution, and pain outcomes both before and after
treatment were also examined in the study. The male-to-
female ratio in Group A was 1:3, whereas the ratio in
Group B was 1:3.75. Both therapies were used, and their
effects in reducing pain were evaluated. The results
showed that both groups had a larger proportion of
females. The groups' age distributions varied, but there
were no statistically significant differences between
them.
Results: The study consisted of 60 patients in total. They
were evenly divided between the two groups. Patients in
group A had a mean age of 59.93 years plus 7.48
standard deviations, whereas those in group B had a
mean age of 61.68 years plus 7.22 SD. After treatment,
when pain levels were compared, Group A reported
4.7+1.31SD of pain, whereas Group B reported
6.03+1.18SD of pain. This difference was statistically
significant using an independent t-test, with a p-value of
0.000. Pre-treatment pain levels between Group A
(mean: 7.93) and Group B (mean: 8.03) were
comparable, and there was little change after therapy. In
contrast, Group A showed a statistically significant
reduction in pain following therapy (mean: 4.7) as
compared to Group B (mean: 6.03).
Conclusion: This study highlights the potential
advantages of intra-articular steroid injections versus
platelet rich plasma injections for the treatment of pain.
Keywords :
Knee Osteoarthritis, Steroid, Platelet Rich Plasma.
