Knee Osteoarthritis: Steriods Verus Platelets Rich Plasma Effectiveness

Authors : Dr. Muhammad Shakeel; Dr. Muhammad Bilal; Dr. Abdullah Jan; Dr. Adnan Khan; Dr. Ubaid Ullah; Dr. Saddam Hussain; Dr. Annas Sani; Dr. Tayyab Mustajab Khan

Volume/Issue : Volume 8 - 2023, Issue 10 - October

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Background: This study compared the effectiveness of two therapy techniques for treating a certain medical condition: intra-articular steroid injection (Group A) and platelet rich plasma injection (Group B). The medial femorotibial compartment, for instance, frequently exhibits the highest decrease of joint space in the osteoarthritic knee. Treatment for osteoarthritis aims to reduce discomfort and enhance functional status. Medium-term improvements are seen with intra- articular platelet-rich plasma, balneotherapy, and whole-body vibration. The study is intended to demonstrate knee osteoarthritis and establish appropriate treatment guidelines. to determine the mean VAS score in individuals with knee osteoarthritis after intra-articular PRP or steroid injection and to evaluate which treatment is more effective at reducing pain for patients with osteoarthritis of the knee: PRP or steroid injections. Methodology: Department of Orthopedics Surgery & Trauma, lady reading hospital peshawer, UPON ETHICAL Comitte Approval. Thirty patients with knee osteoarthritis were studied in each group from 1 JAN 2022 to 31 December 2022. PRP and steroid groups of patients were randomly assigned using randomization through non-probability consecutive sampling. SPSS-24 Version was used to recode and analyze the results of the CONTROL TRIAL. The male-to-female ratio, age distribution, and pain outcomes both before and after treatment were also examined in the study. The male-to- female ratio in Group A was 1:3, whereas the ratio in Group B was 1:3.75. Both therapies were used, and their effects in reducing pain were evaluated. The results showed that both groups had a larger proportion of females. The groups' age distributions varied, but there were no statistically significant differences between them. Results: The study consisted of 60 patients in total. They were evenly divided between the two groups. Patients in group A had a mean age of 59.93 years plus 7.48 standard deviations, whereas those in group B had a mean age of 61.68 years plus 7.22 SD. After treatment, when pain levels were compared, Group A reported 4.7+1.31SD of pain, whereas Group B reported 6.03+1.18SD of pain. This difference was statistically significant using an independent t-test, with a p-value of 0.000. Pre-treatment pain levels between Group A (mean: 7.93) and Group B (mean: 8.03) were comparable, and there was little change after therapy. In contrast, Group A showed a statistically significant reduction in pain following therapy (mean: 4.7) as compared to Group B (mean: 6.03). Conclusion: This study highlights the potential advantages of intra-articular steroid injections versus platelet rich plasma injections for the treatment of pain.

Keywords : Knee Osteoarthritis, Steroid, Platelet Rich Plasma.


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31 - December - 2023

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