Placing an intravenous cannula for children is one of the nurse’s role in emergency, intensive care unit or wards. It can be performed for diagnostic, nutritional or therapeutic reasons. The overall aim of this study was to assess nurses’ knowledge and practice towards peripheral intravenous cannulation in pediatric patients. An interventional hospital-based study design, quantitative approach was selected for this work. The study was conducted in two main public hospitals in Khartoum. The study population were Nurses of all categories who worked in the study area during the study period of data collection (60 nurses). Data collection techniques used are interviewing and observing. Tools used to collect data are questionnaire and observational check list. Data was processed and analyzed by computer program which is SPSS Ver.19.0 The study showed a significant relationship between the educational program and the change in the level of knowledge for nurses who participated in the study as the P.value found to be 0.00 and also significant change in the practice. So the study concluded that: Nurses are motivated to learn as evidenced by the change in their knowledge and practice after implementing the educational program.

Keywords : Intravenous Cannula; Peripheral Intravenous Cannulation; Pediatric.