Low-Intensity Continuous Training Vs. Metformin for Managing Pre-Diabetic Patients


Authors : Dr. T. TULASI RANI; Dr. A. SUDHA RANI; Dr. AANANTHA K N R; Dr. Y. SURESH BABU

Volume/Issue : Volume 8 - 2023, Issue 3 - March

Google Scholar : https://bit.ly/3TmGbDi

Scribd : https://bit.ly/3FSw57S

DOI : https://doi.org/10.5281/zenodo.7776618

Abstract : Pre-diabetes is characterised by the presence of impaired fasting glucose (IFG) and/or impaired glucose tolerance (IGT). [1] Management options for pre-diabetes patients included intake of a low-carbohydrate and low-fat diet along with regular physical exercise and [2] usage of medications like pioglitazone or metformin. Continuous training is physical training that involves activity without resting. This contrasts with interval training, which doesn't involve any rest periods. It includes aerobic activities like walking, running, biking, swimming, water aerobics and rowing. OBJECTIVES: The current study was done to assess the effect of Low-Intensity Continuous Training (LICT) versus Metformin on patients diagnosed to have prediabetes. MATERIAL AND METHODS: This interventional study was carried out at the department of physiology, Government Medical College, Kurnool, Andhra Pradesh, India, during the period of August 2022 to January 2023. Sixty patients were divided into two groups by randomisation. Group A – Included 30 prediabetic adults who were exposed to only LICT for 16 weeks. Group B - Included 30 pre-diabetic adults who were given only Metformin for 16 weeks. Student's Ttest was done to compare the two interventions. RESULTS: Most patients were males aged 51-60 years old. There was a significant improvement in HbA1c, FBG, PPBG over 16 weeks in all 60 patients. Body weight and BMI reduced significantly in both groups. LICT was better in glycaemic control over Metformin in the current study in terms of FBG and PPBG. CONCLUSION: The results indicate that regular physical exercise in the form of LICT could provide better glucose control and controlled body weight than pharmacological treatment in the form of Metformin. More knowledge on glycaemic management in the prediabetic stage can prevent the onset of type-2-diabetes Mellitus in many patients.

Keywords : Pre-diabetes, LICT, Metformin, glycaemic control, T-test

Pre-diabetes is characterised by the presence of impaired fasting glucose (IFG) and/or impaired glucose tolerance (IGT). [1] Management options for pre-diabetes patients included intake of a low-carbohydrate and low-fat diet along with regular physical exercise and [2] usage of medications like pioglitazone or metformin. Continuous training is physical training that involves activity without resting. This contrasts with interval training, which doesn't involve any rest periods. It includes aerobic activities like walking, running, biking, swimming, water aerobics and rowing. OBJECTIVES: The current study was done to assess the effect of Low-Intensity Continuous Training (LICT) versus Metformin on patients diagnosed to have prediabetes. MATERIAL AND METHODS: This interventional study was carried out at the department of physiology, Government Medical College, Kurnool, Andhra Pradesh, India, during the period of August 2022 to January 2023. Sixty patients were divided into two groups by randomisation. Group A – Included 30 prediabetic adults who were exposed to only LICT for 16 weeks. Group B - Included 30 pre-diabetic adults who were given only Metformin for 16 weeks. Student's Ttest was done to compare the two interventions. RESULTS: Most patients were males aged 51-60 years old. There was a significant improvement in HbA1c, FBG, PPBG over 16 weeks in all 60 patients. Body weight and BMI reduced significantly in both groups. LICT was better in glycaemic control over Metformin in the current study in terms of FBG and PPBG. CONCLUSION: The results indicate that regular physical exercise in the form of LICT could provide better glucose control and controlled body weight than pharmacological treatment in the form of Metformin. More knowledge on glycaemic management in the prediabetic stage can prevent the onset of type-2-diabetes Mellitus in many patients.

Keywords : Pre-diabetes, LICT, Metformin, glycaemic control, T-test

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