Authors :
Dr. J. G. Bhatt; Dr. J. G. Vagadia; Dr. Manisha Nakum
Volume/Issue :
Volume 10 - 2025, Issue 6 - June
Google Scholar :
https://tinyurl.com/hjn8ddxj
DOI :
https://doi.org/10.38124/ijisrt/25jun217
Note : A published paper may take 4-5 working days from the publication date to appear in PlumX Metrics, Semantic Scholar, and ResearchGate.
Abstract :
Introduction and Significance:
Mycetoma / Madura foot, is a chronic , progressive granulomatous condition affecting the skin , subcutaneous tissue
and bones. It is primarily caused by fungi or anaerobic filamentous bacteria and is prevalent in tropical and subtropical
regions, particularly among males aged 20-50 years who are exposed to outdoor environments, especially farmers.
Case Presentation:
We report the case of a 50 year old male patient with history of fieldwork with early presentation as swelling over right
foot medial aspect with symptoms of minimal discharge from sinuses, fibrosis and induration.
Clinical Discussion:
Madura foot is one of the neglected tropical disease characterized by localized soft tissue injury with discharge grains
containing infectious material. Fungal induced cases are termed eumycetomas, while bacterial forms caused by
actinomycetes are referred to as actinomycetomas. Diagnosis typically relies on clinical evaluation, radiolographic findings
and microscopic/histopathological examination.surgical excision of lesion combined with medical therapy is often the most
effective treatment.
Conclusion:
Madura foot is long-standing infection commonly found in tropical and subtropical regions such as india .due to its
varied presentation,diagnosis of madura foot can be challenging, however ,culture remains the gold standard diagnostic test
, histopathology is crucial for the early diagnosis and definitive treatment of these cases . actinomycetoma can be cured
with surgical debridement and appropriate antibiotic therapy while eumycetoma is only partially responsive to antifungal
agents has high rate of recurrence and may require amputation.
Keywords :
Madura Foot, Mycetoma, Eumycetoma, Actinomycosis, Black Grains, Investigations, Management.
References :
- Azzoni R, Capitza P; Madura’s foot in native of the Philippines immigrant in northern Italy.J Orthop., 2005; 2(6): 1-6.
- Alam K, Maheshwari V, Bhargava S, Jain A, Fatima U, Haq EU. Histological diagnosis of madura foot (mycetoma): a must for definitive treatment. J Glob Infect Dis. 2009 Jan;1(1):64-7. doi: 10.4103/0974-777X.52985. [PubMed]
- Davis JD, Stone PA, McGarry JJ. Recurrent mycetoma of the foot. J Foot Ankle Surg. 1999 Jan-Feb;38(1):55-60. [PubMed]
- Fahal AH. Mycetoma: a thorn in the flesh. Trans R Soc Trop Med Hyg. 2004 Jan;98(1):3-11. [PubMed Iffat H, Abid K. Mycetoma Revisited. NDermatol Online, 2011; 2(3): 147-150.
- Mohammad N, Arif C, Ruksana P, Rokon U,Abdur R, Moydul H; The Madura foot. A CaseReport. N Dermatol Online, 2011; 2(2): 70-73.
- Negroni R, Lopez Daneri G, Arechavala A,Bianchi MH, Robles AM; Clinical and microbiological study of mycetomas at theMuniz Hospital of Buenos Aires between 1989 and 2004. Rev Argent Microbiol., 2006; 38(1):13-18. [PubMed]
- Pilsczek FH, Augenbraun M. Mycetoma fungal infection: multiple organisms as colonizers or pathogens? Rev Soc Bras Med Trop. 2007 Jul-Aug;40(4):463-5. [PubMed]
- van de Sande WW, de Kat J, Coppens J, Ahmed AO, Fahal A, Verbrugh H, van Belkum A. Melanin biosynthesis in Madurella mycetomatis and its effect on susceptibility to itraconazole and ketoconazole. Microbes Infect. 2007 Jul;9(9):1114-23. Epub 2007 May
- V Lichon, A Khachemoune Mycetoma: a review Am J Clin Dermatol, 7 (2006), pp. 315-321 View at publisherCrossrefView in ScopusGoogle Scholar
- V Jain, GE Makwana, N Bahri, MK Mathur The “dot in circle” sign on MRI in maduramycosis: a characteristic finding J Clin Imaging Sci, 2 (2012), pp. 66-67 View at publisherCrossrefGoogle Scholar
- S Venkatswami, A Sankarasubramanian, S Subramanyam The Madura foot: look
Introduction and Significance:
Mycetoma / Madura foot, is a chronic , progressive granulomatous condition affecting the skin , subcutaneous tissue
and bones. It is primarily caused by fungi or anaerobic filamentous bacteria and is prevalent in tropical and subtropical
regions, particularly among males aged 20-50 years who are exposed to outdoor environments, especially farmers.
Case Presentation:
We report the case of a 50 year old male patient with history of fieldwork with early presentation as swelling over right
foot medial aspect with symptoms of minimal discharge from sinuses, fibrosis and induration.
Clinical Discussion:
Madura foot is one of the neglected tropical disease characterized by localized soft tissue injury with discharge grains
containing infectious material. Fungal induced cases are termed eumycetomas, while bacterial forms caused by
actinomycetes are referred to as actinomycetomas. Diagnosis typically relies on clinical evaluation, radiolographic findings
and microscopic/histopathological examination.surgical excision of lesion combined with medical therapy is often the most
effective treatment.
Conclusion:
Madura foot is long-standing infection commonly found in tropical and subtropical regions such as india .due to its
varied presentation,diagnosis of madura foot can be challenging, however ,culture remains the gold standard diagnostic test
, histopathology is crucial for the early diagnosis and definitive treatment of these cases . actinomycetoma can be cured
with surgical debridement and appropriate antibiotic therapy while eumycetoma is only partially responsive to antifungal
agents has high rate of recurrence and may require amputation.
Keywords :
Madura Foot, Mycetoma, Eumycetoma, Actinomycosis, Black Grains, Investigations, Management.