Making and Assessing an Antibacterial Cream with Dalbergia Sissoo Leaf Extract


Authors : Tushar Pukale; Swapnali More; Sujan Mulla; Subhan Shaikh; Sonali Maharnawar; Vishal Ghadge

Volume/Issue : Volume 9 - 2024, Issue 5 - May

Google Scholar : https://tinyurl.com/mt3j26ff

Scribd : https://tinyurl.com/2s4be4yz

DOI : https://doi.org/10.38124/ijisrt/IJISRT24MAY2209

Abstract : Medicinal plants are still a valuable therapeutic resource for treating human illnesses. The plant Dalbergia sissoo is important to the health care system and includes several chemical constituents that have particular importance in traditional medical practices. This study's primary goal is to assess the ethanol extracts from D. sissoo leaves' antibacterial activity. Using ethanol, the dried leaves of Dalbergia sissoo are extracted. Additionally, the extract's phytochemical screening was completed. The ethanolic extract was then used to make the herbal antibacterial cream composition. Examine the cream's physical characteristics as well. Using the disc diffusion method with bioassay guidance, the assay was conducted on Staphylococcus aureus. Staphylococcus aureus bacteria, both gram positive (+) and gram negative (-), were utilised to measure the antibacterial activity of the cream.

Keywords : Dalbergia Sissoo, Staphylococcus Aureus, Triterpenoids, Phytochemical Screening, Leaves Extract, Ethanolic Extract, Wound Healing Activity, Antiinflammatory Activity, Antioxidant Activity.

References :

  1. T. Muthu Lakshmi, R. Radha, N. Jayshree (2014). Formulation And Evaluation of Herbal Gel Containing Dalbergia Sissoo Roxb. Bark Extract. Journal of pharmaceutical research and clinical practice, 4 (1), 53-57. https://www.rroij.com/open-access/formulation-and-evaluation-of-herbal-gel-conatining-dalbergia-sissoo-roxb-bark-extract.pdf
  2. M. Bharath, E. Laxmi Rama Tulasi, K. Sudhakar and M. Chinna Eswaraiah (2013). Dalbergia sissoo DC. – An Important Medicinal Plant. International journal of research in pharmacy and chemistry, 3 (2), 384-388. https://www.ijrpc.com/files/32-3111.pdf
  3. Manoj D. Jadhav, Mangesh P. Ubale, Shubham V. Kadam, Ansari M. Ehtesham (2023). Formulation And Evaluation of Herbal Skin Cream for Wound Healing Activity. International research journal of pharmacy and medical sciences, 6 (4), 8-12. http://repository-tnmgrmu.ac.in/6609/1/260107917jamshiyashamsu.pf
  4. Sangram K. Panda, Ram P. Padhy, Gayatri D. Rout Ray and Subhashree. Padhy (2016). Phytochemical Investigation and Evaluation of Wound Healing Potential of Crude Leave Extract of Dalbergia Sissoo (Roxb.), In Wister Rats. World journal of pharmaceutical research, 5 (1), 1528-1534. https://www.cabidigitallibrary.org/doi/full/10.5555/20163075063
  5. T. Muthu Lakshmi, R. Radha, N. Jayshree (2014). Formulation And Evaluation of Herbal Gel Containing Dalbergia Sissoo Roxb. Bark Extract. Journal of pharmaceutical research and clinical practice, 4 (1), 53-57. https://www.rroij.com/open-access/formulation-and-evaluation-of-herbal-gel-conatining-dalbergia-sissoo-roxb-bark-extract.pdf
  6. Md. Abdul Mannan, Ambia Khatun and Md. Farhad Hossen Khan (2017). Antinociceptive Effect of Methanol Extract of Dalbergia Sissoo Leaves in Mice. BMC complementary and alternative medicine, 17 (72) 1-13. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5260076/
  7. Ali Esmail al-snafi (2017). Chemical Constituents and Pharmacological Effects of Dalbergia sissoo – A review. IOSR journal of pharmacy, 7 (2), 59-71. https://www.researchgate.net/publication/313823368_Chemical_constituents_and_pharmacological_effects_of_Dalbergia_sissoo_-A_review
  8. Vyshali Karthikeyan, Vickram Sundaram, Ramesh Pathy Maniyan, Sridharan Balasundaram (2016). Formulation of Herbal Emulsion based Antiinflammatory Cream for Skin Diseases. International Journal of Pharmaceutical Sciences Review and Research, 40 (2), 215-220. https://www.researchgate.net/publication/310488140_Formulation_of_herbal_emulsion_based_antiinflammatory_cream_for_skin_diseases
  1. Mohammad Asif, Arun Kumar (2009). AntiInflammatory Activity of Ethanolic Extract of Dalbergia Sissoo (Roxb.) Bark. Malaysian Journal of Pharmaceutical Sciences, 7 (1), 39–50. https://www.researchgate.net/publication/44003822_AntiInflammatory_activity_of_ethanolic_Extract_of_dalbergia_sissoo_Roxb_bark
  2. K. Wimalasooriya, M. J. Gunaratna (2023). Formulation And Evaluation of The AntiInflammatory Activity of An Herbal Cream Utilizing Curcuma Longa L. (Turmeric) And Elaeocarpus Serratus L. (Ceylon Olive). International Conference on Applied and Pure Sciences, 3 (1), 168. http://repository.kln.ac.lk/handle/123456789/27008
  3. Shipra Singh, Harshita Jain, Parul Vyas, Nitin Nama (2022). Formulation And Evaluation of Multifunction General Use Cream. Career point international journal of research, 1 (2), 69-81. http://cpijr.com/vol-1%20issue-2/paper-5.pdf
  4. Nikhil Nitin Navindgikar, K. A. Kamalapurkar, Prashant S. Chavan (2020). Formulation And Evaluation of Multipurpose Herbal Cream. International journal of current pharmaceutical research, 12 (3), 25-30. https://journals.innovareacademics.in/index.php/ijcpr/article/view/38300/22576
  5. Vidyadhara Suryadevara, Sandeep Doppalapudi, Sasidhar Reddivallam L. 40(2Formulation And Evaluation of Anti Inflammatory Cream by Using Moringa Oleifera Seed Oil. Pharmacognosy research, 10 (2), 195-204. https://www.researchgate.net/publication/324979156_Formulation_and_evaluation_of_antiinflammatory_cream_by_using_Moringa_oleifera_seed_oil
  6. Nikhil Nitin Navindgikar, K. A. Kamalapurkar, Prashant S. Chavan (2020). Formulation And Evaluation of Multipurpose Herbal Cream. International journal of current pharmaceutical research, 12 (3), 25-30. https://journals.innovareacademics.in/index.php/ijcpr/article/view/38300/22576
  7. Vidyadhara Suryadevara, Sandeep Doppalapudi, Sasidhar Reddivallam L. C, Ramu Anne, Mounika Mudda (2021). Formulation And Evaluation of Anti Inflammatory Cream by Using Moringa Oleifera Seed Oil. Pharmacognosy research, 10 (2), 195- 204. https://www.researchgate.net/publication/324979156_Formulation_and_evaluation_of_antiinflammatory_cream_by_using_Moringa_oleifera_seed_oil
  8. Nikhil Nitin Navindgikar, K. A. Kamalapurkar, Prashant S. Chavan (2020). Formulation And Evaluation of Multipurpose Herbal Cream. International journal of current pharmaceutical research, 12 (3), 25-30. https://journals.innovareacademics.in/index.php/ijcpr/article/view/38300/22576
  1. Rohit Kumar Bijauliya, S. K. Jain, Shashi Alok, V.K. Dixit, Vijay Kumar Singh and Man Singh (2017). Macroscopical, Microscopical and Physico-Chemical Studies on Leaves of Dalbergia Sissoo Linn. (Fabaceae). International Journal of Pharmaceutical Sciences and Research, 8 (4), 1865-1873. https://ijpsr.com/bft-article/macroscopical-microscopical-and-physico-chemical-studies-on-leaves-of-dalbergia-sissoo-linn%20fabaceae/?view=fulltext
  2. Gaurab Subedi, Chandan Kumar Sah, Dinesh Kumar Joshi Pokharel, Mukesh Kumar Chaudhary, Pramod Aryal, Ishwar Bhandari and Ravin Bhandari (2017). Anti - Bacterial Guided Fractionation of Dalbergia Sissoo. International Journal of Pharmaceutical Sciences and Research, 8 (10), 4325-4334. https://ijpsr.com/?action=download_pdf&postid=36988
  3. Mahendran Sekar, Nur Syahira Abdul Jalil (2017). Formulation and Evaluation of Novel Antibacterial and AntiInflammatory Cream Containing MuntingiaCalabura Leaves Extract. Asian Journal of Pharmaceutical and Clinical Research, 10 (12), 376-379. https://doi.org/10.22159/ajpcr.2017.v10i12.21963
  4. Gaurab Subedi, Chandan Kumar Sah, Dinesh Kumar Joshi Pokharel, Mukesh Kumar Chaudhary, Pramod Aryal, Ishwar Bhandari and Ravin Bhandari (2017). Anti - Bacterial Guided Fractionation of Dalbergia Sissoo. International Journal of Pharmaceutical Sciences and Research, 8 (10), 4325-4334. https://ijpsr.com/?action=download_pdf&postid=36988

Medicinal plants are still a valuable therapeutic resource for treating human illnesses. The plant Dalbergia sissoo is important to the health care system and includes several chemical constituents that have particular importance in traditional medical practices. This study's primary goal is to assess the ethanol extracts from D. sissoo leaves' antibacterial activity. Using ethanol, the dried leaves of Dalbergia sissoo are extracted. Additionally, the extract's phytochemical screening was completed. The ethanolic extract was then used to make the herbal antibacterial cream composition. Examine the cream's physical characteristics as well. Using the disc diffusion method with bioassay guidance, the assay was conducted on Staphylococcus aureus. Staphylococcus aureus bacteria, both gram positive (+) and gram negative (-), were utilised to measure the antibacterial activity of the cream.

Keywords : Dalbergia Sissoo, Staphylococcus Aureus, Triterpenoids, Phytochemical Screening, Leaves Extract, Ethanolic Extract, Wound Healing Activity, Antiinflammatory Activity, Antioxidant Activity.

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