Management and Immediate Maternal & Neonatal Outcomes of Pre-Labour Rupture of Membranes (PROM) at Ompada Teaching Hospital


Authors : Abd Elslam Salah Eldin Abd Elslam Elhilu; Mogadam Baher-Eldin Yagob; Asma Mohammed Ibraheem Saeed; Azza Hassan Siddig Amin; Munir Abdelrazig Mukhtar Mohammed; Abdelrahman Faisal Suliman Mohamed; Seddig Mohammed Abdella Ali; Baraa Isamaldeen Abdalmounium Mousa

Volume/Issue : Volume 10 - 2025, Issue 6 - June


Google Scholar : https://tinyurl.com/3p69y6ut

DOI : https://doi.org/10.38124/ijisrt/25jun914

Note : A published paper may take 4-5 working days from the publication date to appear in PlumX Metrics, Semantic Scholar, and ResearchGate.


Abstract : Background: Pre-labour rupture of membranes (PROM) is a rupture of the membranes prior to the onset of labour at or beyond 37 weeks gestation. The study aimed to assess the management and immediate maternal & neonatal outcomes of pre- labour rupture of membranes at term.  Methods: A Cohort prospective base study conducted among pregnant women at term attended to the emergency department complained of drainage of liquor at Ompada teaching hospital. The data were collected by structured questionnaire filled through direct face to face interviews after obtained informed consent.  Results: Out of 150 pregnant women were included in the final analysis of pre-labour rupture of membranes at term, the mean age of included women was 28.5 (range between 18-37 years) with majority cases were multigravidas. About 19.3% of the cases were un-booked with 32.7% of them had similar condition of PROM and 20.7% of the cases had previous history of preterm delivery on the past. About 17.3% of the cases chosen the Expectant management and the second group managed by immediate delivery (82.7%) either by Caesarian section (33.8%) or by Acceleration (66.2%). There was no statistically significant difference between postpartum maternal health and plan for delivery (p value 0.133). On the neonatal health, 81.3% of them delivered alive.  Conclusions: The main risk factors that contributed on development of PROM was lower urinary tract infections. The mode of delivery is either planned early induction or expectant management, depend on the conditions of the patients and the cervical favorability, with increase rates of caesarean section in expectant. Early acceleration and induction are recommended to decrease the interval of PROM and the risk of sepsis. Early diagnosis and prompt management is required for better outcome for mother and baby.

Keywords : Pre-Labour Rupture of Membranes, Term, Sudan, Ompada, Management.

References :

  1. Royal Australian and New Zealand College of obstetricians and gynaecologists Board. Term Pre-labour Rupture of Membranes. Women’s Health Committee - RANZCOG website 2017 March.
  2. Nagaria T, Diwan C, Jaiswal J. A study on feto-maternal outcome in patients with premature rupture of membranes. Int J Reprod Contracept Obstet Gynecol 2016 Dec, 5(12); 4123-4127.
  3. Okazaki T, Casey ML, Okita JR, MacDonald PC, Johnson JM. Initiation of human parturition: Biosynthesis and metabolism of prostaglandins in human fetal membranes and uterine decidua. Am J Obstet Gynecol 1981, 139, 373–381.
  4. Ladfors L, Mattsson LA, Eriksson M, Milsom I. Pre-labour rupture of the membranes at or near term, Clinical and epidemiological studies- Perinatal center Department of Obstetrics and Gynaecology Sahlgrenska University Hospital Göteborg, Sweden, 1998.
  5. Fortner KB, Szymanski LM, Fox HE, Wallach EE. Hopkins Manual of Gynecology and Obstetrics, The, 3rd Edition johns - Department of Gynecology and Obstetrics, the Johns Hopkins University School of Medicine, Baltimore, Maryland.
  6. Green-top Guideline. Prevention of Early-onset Neonatal Group B Streptococcal Disease. [Serial online]. September 2017 [Cited 2019 May]; Available from: URL: http://www.rcog.org.uk/en/guidelines-research-services/guidelines/gtg
  7. Khodry MM, Mohammed H, Abdellah AH. Maternal and Neonatal Outcomes of Expectantly Managed Pregnancies of Healthy Cases with Previable Rupture of Membranes at Qena University Hospital. Egypt J Fertil Steril 2025, 29(1).
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  9. Wolde M, Mulatu T, Alemayehu G, Alemayehu A, Assefa N. Predictors and perinatal outcomes of pre-labor rupture of membrane among pregnant women admitted to Hiwot Fana Comprehensive Specialized University Hospital, Eastern Ethiopia: a retrospective study. Front. Med 2024, 10; 1269024. doi: 10.3389/fmed.2023.1269024.
  10. Shakya A, Gupta SK. Neonatal outcome of maternal premature rupture of membranes more than 18 hours. Journal of Kathmandu Medical College 2020, 9(2), 81-86.
  11. Naveen Chandra S, Pradeep MR, Shashikumara. Maternal and Neonatal Outcomes and the Associated Risk Factors for Premature Rupture of Membranes. Journal of South Asian Federation of Obstetrics and Gynaecology 2020, 12 (6). 403-407.

Background: Pre-labour rupture of membranes (PROM) is a rupture of the membranes prior to the onset of labour at or beyond 37 weeks gestation. The study aimed to assess the management and immediate maternal & neonatal outcomes of pre- labour rupture of membranes at term.  Methods: A Cohort prospective base study conducted among pregnant women at term attended to the emergency department complained of drainage of liquor at Ompada teaching hospital. The data were collected by structured questionnaire filled through direct face to face interviews after obtained informed consent.  Results: Out of 150 pregnant women were included in the final analysis of pre-labour rupture of membranes at term, the mean age of included women was 28.5 (range between 18-37 years) with majority cases were multigravidas. About 19.3% of the cases were un-booked with 32.7% of them had similar condition of PROM and 20.7% of the cases had previous history of preterm delivery on the past. About 17.3% of the cases chosen the Expectant management and the second group managed by immediate delivery (82.7%) either by Caesarian section (33.8%) or by Acceleration (66.2%). There was no statistically significant difference between postpartum maternal health and plan for delivery (p value 0.133). On the neonatal health, 81.3% of them delivered alive.  Conclusions: The main risk factors that contributed on development of PROM was lower urinary tract infections. The mode of delivery is either planned early induction or expectant management, depend on the conditions of the patients and the cervical favorability, with increase rates of caesarean section in expectant. Early acceleration and induction are recommended to decrease the interval of PROM and the risk of sepsis. Early diagnosis and prompt management is required for better outcome for mother and baby.

Keywords : Pre-Labour Rupture of Membranes, Term, Sudan, Ompada, Management.

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