This paper sets out the results of research on uses and customs in relation to medicinal plants. It was held in Comitán de Domínguez, Chiapas, Mexico, a middle city located in an area bordering the Republic of Guatemala. In this country, the use of medicinal plants is an important part of culture from origin to the present day, despite the relevance of allopathic medicine and the pharmaceutical industry that supports it. The uses and customs related to the health care of the Mayan peoples are based on the great diversity of flora and fauna of the region. Specifically, medicinal plants are commonly used and are mostly cultivated by families for self-consumption.

Keywords : Medicinal Plants, Chiapas, Traditional Practices.