Authors :
Dr. Prachi Kalra; Dr. Harsh Aggarwal
Volume/Issue :
Volume 7 - 2022, Issue 11 - November
Google Scholar :
https://bit.ly/3IIfn9N
DOI :
https://doi.org/10.5281/zenodo.7439972
Abstract :
Adenoid cystic carcinoma (ACC) is rare
neoplasia of salivary glands, constitutes 7-10% of salivary
gland neoplasms. It occurs in both major and minor
salivary glands however found in other sites like head and
neck, lung, breast, female genital tract, prostate and skin.
It is a slow-growing tumour with gradual evolution, quite
aggressive locally with perineural spread, tendency
towards local recurrence and distant metastasis. This is a
case report and review analysis of adenoid cystic
carcinoma of salivary gland and other sites. Hereby we
report a 53-year-old female, post-operative case of
adenoid cystic carcinoma of submandibular gland
remained asymptomatic for 6 years after treatment with
radiotherapy alone, now developed metastases to lung.
Performance status is 2 therefore metastasis was
challenged with Adriamycin based chemotherapy. After
four cycles of chemotherapy desired response was not
achieved hence palliative radiotherapy to lung lesion was
planned.
Keywords :
Adenoid Cystic Carcinoma, Cribriform Pattern, Submandibular Gland.
Adenoid cystic carcinoma (ACC) is rare
neoplasia of salivary glands, constitutes 7-10% of salivary
gland neoplasms. It occurs in both major and minor
salivary glands however found in other sites like head and
neck, lung, breast, female genital tract, prostate and skin.
It is a slow-growing tumour with gradual evolution, quite
aggressive locally with perineural spread, tendency
towards local recurrence and distant metastasis. This is a
case report and review analysis of adenoid cystic
carcinoma of salivary gland and other sites. Hereby we
report a 53-year-old female, post-operative case of
adenoid cystic carcinoma of submandibular gland
remained asymptomatic for 6 years after treatment with
radiotherapy alone, now developed metastases to lung.
Performance status is 2 therefore metastasis was
challenged with Adriamycin based chemotherapy. After
four cycles of chemotherapy desired response was not
achieved hence palliative radiotherapy to lung lesion was
planned.
Keywords :
Adenoid Cystic Carcinoma, Cribriform Pattern, Submandibular Gland.
