Authors :
Dr. Richa Sharma; Dr. Rekha Mehrotra; Payal Mago
Volume/Issue :
Volume 8 - 2023, Issue 4 - April
Google Scholar :
https://bit.ly/3TmGbDi
Scribd :
https://bit.ly/3VKCrwD
DOI :
https://doi.org/10.5281/zenodo.7902165
Abstract :
Keratinase are special proteases which have
the ability to degrade recalcitrant, proteinase K resistant
proteins. They are elaborated by compendium of microorganisms that include bacteria, actinomycetes and fungi.
The keratinase research can be divided into three phases.
The first phase from was completely dominated by Ker A
involving work on its characterization, production,
expression and application. The establishment of Ker A
as a biotechnologically important enzyme gave way to the
second phase of research wherein scientists started
exploring the diversity of keratinolytic micro-organisms
and understanding its role in keratin degradation. The
third phase came with the revealation of its ability to
degrade recalcitrant prion protein. Since then, there have
been increasing number of reports on keratinases and
their characterization. The present article elaborates the
journey of keratinase research starting from its
establishment as a special protease to the present-day
advancements.
Keywords :
Keratinase, Protease, Sustainability, Feather Degraation, Prion Degradation, Ungual Enhancer.
Keratinase are special proteases which have
the ability to degrade recalcitrant, proteinase K resistant
proteins. They are elaborated by compendium of microorganisms that include bacteria, actinomycetes and fungi.
The keratinase research can be divided into three phases.
The first phase from was completely dominated by Ker A
involving work on its characterization, production,
expression and application. The establishment of Ker A
as a biotechnologically important enzyme gave way to the
second phase of research wherein scientists started
exploring the diversity of keratinolytic micro-organisms
and understanding its role in keratin degradation. The
third phase came with the revealation of its ability to
degrade recalcitrant prion protein. Since then, there have
been increasing number of reports on keratinases and
their characterization. The present article elaborates the
journey of keratinase research starting from its
establishment as a special protease to the present-day
advancements.
Keywords :
Keratinase, Protease, Sustainability, Feather Degraation, Prion Degradation, Ungual Enhancer.
