Authors :
Samuel Danley; Daniel Laban; Olugbami Elizabeth Oluwatosin; Faith Dedan Nyari; Simon Jude Jatutu
Volume/Issue :
Volume 11 - 2026, Issue 3 - March
Google Scholar :
https://tinyurl.com/2s3dyurs
Scribd :
https://tinyurl.com/5n8rvtab
DOI :
https://doi.org/10.38124/ijisrt/26mar302
Note : A published paper may take 4-5 working days from the publication date to appear in PlumX Metrics, Semantic Scholar, and ResearchGate.
Abstract :
Micronutrient deficiencies (MNDs)—including iron-deficiency anemia, vitamin A deficiency, iodine deficiency
and zinc deficiency—continue to be a complex problem in Sub-Saharan Africa (SSA) that disproportionately burdens
women of childbearing age, infants and young children, as well as other vulnerable populations. The following three
consumer staples—universal salt iodization (USI), flour fortification, and edible oil fortification—and large-scale food
fortification (LSFF) have been recognized as cost-effective interventions. Despite such efforts however, progress has been
uneven, with gaps and weak enforcement of legal instruments, poor monitoring systems, unequal coverage and donor
dependency in financing minimizing the impact. There is progress, for example decreases in neural tube defects in South
Africa and improved iodine sufficiency in certain countries, but wider reductions in anemia and vitamin A deficiency remain
erratic. There is a strong equity dimension involved, notably because urban and wealthy groups benefit more than rural
and marginalized ones. New solutions — biofortification of staple crops, digital surveillance platforms and enhanced public-
-private collaborations -- hold the potential to address these gaps, but their long-term sustainability and integration with
other nutrition strategies need to be investigated. This scoping review assesses the evidence on the applicability, effective
coverage and policy implications of fortification in SSA while highlighting best practices for success, ongoing challenges and
research priorities to guide future nutrition policy and programming.
Keywords :
Micronutrient Deficiencies; Food Fortification; Equity; Sub-Saharan Africa; Anemia; Biofortification; Nutrition Policy; Public–Private Partnerships.
References :
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- Rohner, F., Garrett, G. S., & Osendarp, S. (2023). Global coverage of mandatory large-scale food fortification: Reach of salt, wheat flour, edible oil, maize flour, and rice. Global Food Security, 39, 100678. https://doi.org/10.1016/j.gfs.2023.100678
- Khamila, S., Okoth, M. W., & Abong, G. O. (2020). Compliance status and stability of vitamins and minerals in fortified maize flour in Kenya. Current Research in Food Science, 3, 100–108. https://doi.org/10.1016/j.crfs.2020.100108
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- Mkambula, P., et al. (2020). The unfinished agenda for food fortification in low- and middle-income countries: Quantifying progress, gaps, and potential opportunities. Nutrients, 12(2), 354. https://doi.org/10.3390/nu12020354
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- Osendarp, S., Martinez, H., Garrett, G. S., Neufeld, L. M., & de-Regil, L. M. (2021). Large-scale food fortification and biofortification in low- and middle-income countries: A review of programs, trends, challenges, and evidence gaps. Food and Nutrition Bulletin, 42(1), 3–24. https://doi.org/10.1177/0379572121991455
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- Fiedler, J. L., Lividini, K., Zulu, R., Kabaghe, G., Tehinse, J., Bermudez, O. I., & Smitz, M. F. (2013). Identifying Zambia’s industrial fortification options: Toward reaching feasibility. Food and Nutrition Bulletin, 34(4), 501–519. https://doi.org/10.1177/156482651303400407
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- Rohner, F., Garrett, G. S., & Osendarp, S. (2023). Global coverage of mandatory large-scale food fortification: Reach of salt, wheat flour, edible oil, maize flour, and rice. Global Food Security, 39, 100678. https://doi.org/10.1016/j.gfs.2023.100678
- Mkambula, P., et al. (2020). The unfinished agenda for food fortification in low- and middle-income countries: Quantifying progress, gaps, and potential opportunities. Nutrients, 12(2), 354. https://doi.org/10.3390/nu12020354
- Osendarp, S., Martinez, H., Garrett, G. S., Neufeld, L. M., & de-Regil, L. M. (2021). Large-scale food fortification and biofortification in low- and middle-income countries: A review of programs, trends, challenges, and evidence gaps. Food and Nutrition Bulletin, 42(1), 3–24. https://doi.org/10.1177/0379572121991455
- Luthringer, C. L., Rowe, L. A., Vossenaar, M., & Garrett, G. S. (2015). Regulatory monitoring of fortified foods: Identifying barriers and good practices. Global Health: Science and Practice, 3(3), 446–461. https://doi.org/10.9745/GHSP-D-15-00171
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- UNICEF. (2025). State of the World’s Children Data: Nutrition. Retrieved from https://data.unicef.org/topic/nutrition/
- Khamila, S., Okoth, M. W., & Abong, G. O. (2020). Compliance status and stability of vitamins and minerals in fortified maize flour in Kenya. Current Research in Food Science, 3, 100–108. https://doi.org/10.1016/j.crfs.2020.100108
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- Horton, S., Mannar, V., & Wesley, A. (2008). Food fortification with iron and folic acid: Costs, benefits, and financing. Geneva: WHO.
- Mkambula, P., et al. (2020). The unfinished agenda for food fortification in low- and middle-income countries: Quantifying progress, gaps, and potential opportunities. Nutrients, 12(2), 354. https://doi.org/10.3390/nu12020354
- Allen, L., de Benoist, B., Dary, O., & Hurrell, R. (2006). Guidelines on food fortification with micronutrients. Geneva: World Health Organization & Food and Agriculture Organization.
- Pachón, H., Spohrer, R., Mei, Z., & Serdula, M. K. (2015). Evidence of the effectiveness of flour fortification programs on iron status and anemia: A systematic review. Nutrition Reviews, 73(11), 780–795. https://doi.org/10.1093/nutrit/nuv037
- Osendarp, S., Martinez, H., Garrett, G. S., Neufeld, L. M., & de-Regil, L. M. (2021). Large-scale food fortification and biofortification in low- and middle-income countries: A review of programs, trends, challenges, and evidence gaps. Food and Nutrition Bulletin, 42(1), 3–24. https://doi.org/10.1177/0379572121991455
- Mkambula, P., et al. (2020). The unfinished agenda for food fortification in low- and middle-income countries: Quantifying progress, gaps, and potential opportunities. Nutrients, 12(2), 354. https://doi.org/10.3390/nu12020354
- Luthringer, C. L., Rowe, L. A., Vossenaar, M., & Garrett, G. S. (2015). Regulatory monitoring of fortified foods: Identifying barriers and good practices. Global Health: Science and Practice, 3(3), 446–461. https://doi.org/10.9745/GHSP-D-15-00171
- Global Alliance for Improved Nutrition (GAIN). (2022). Large-Scale Food Fortification Compliance in Nigeria: State of the Nation Report. Geneva: GAIN.
- Horton, S., Mannar, V., & Wesley, A. (2008). Food fortification with iron and folic acid: Costs, benefits, and financing. Geneva: World Health Organization.
- Allen, L., de Benoist, B., Dary, O., & Hurrell, R. (2006). Guidelines on food fortification with micronutrients. Geneva: WHO/FAO.
- UNICEF. (2025). State of the World’s Children Data: Nutrition. Retrieved from https://data.unicef.org/topic/nutrition/
- Pachón, H., Spohrer, R., Mei, Z., & Serdula, M. K. (2015). Evidence of the effectiveness of flour fortification programs on iron status and anemia: A systematic review. Nutrition Reviews, 73(11), 780–795. https://doi.org/10.1093/nutrit/nuv037
- Osendarp, S., Martinez, H., Garrett, G. S., Neufeld, L. M., & de-Regil, L. M. (2021). Large-scale food fortification and biofortification in low- and middle-income countries: A review of programs, trends, challenges, and evidence gaps. Food and Nutrition Bulletin, 42(1), 3–24. https://doi.org/10.1177/0379572121991455
- Mkambula, P., et al. (2020). The unfinished agenda for food fortification in low- and middle-income countries: Quantifying progress, gaps, and potential opportunities. Nutrients, 12(2), 354. https://doi.org/10.3390/nu12020354
- Luthringer, C. L., Rowe, L. A., Vossenaar, M., & Garrett, G. S. (2015). Regulatory monitoring of fortified foods: Identifying barriers and good practices. Global Health: Science and Practice, 3(3), 446–461. https://doi.org/10.9745/GHSP-D-15-00171
- Global Alliance for Improved Nutrition (GAIN). (2022). Large-Scale Food Fortification Compliance in Nigeria: State of the Nation Report. Geneva: GAIN.
- Horton, S., Mannar, V., & Wesley, A. (2008). Food fortification with iron and folic acid: Costs, benefits, and financing. Geneva: World Health Organization.
- Allen, L., de Benoist, B., Dary, O., & Hurrell, R. (2006). Guidelines on food fortification with micronutrients. Geneva: WHO/FAO.
- UNICEF. (2025). State of the World’s Children Data: Nutrition. Retrieved from https://data.unicef.org/topic/nutrition/
- World Health Organization. (2025, February 10). Anaemia (Fact sheet). https://www.who.int/news-room/fact-sheets/detail/anaemia
- UNICEF. (2025). State of the World’s Children Data: Nutrition. Retrieved from https://data.unicef.org/topic/nutrition/
- Rohner, F., Garrett, G. S., & Osendarp, S. (2023). Global coverage of mandatory large-scale food fortification: Reach of salt, wheat flour, edible oil, maize flour, and rice. Global Food Security, 39, 100678. https://doi.org/10.1016/j.gfs.2023.100678
- Mkambula, P., et al. (2020). The unfinished agenda for food fortification in low- and middle-income countries: Quantifying progress, gaps, and potential opportunities. Nutrients, 12(2), 354. https://doi.org/10.3390/nu12020354
- Osendarp, S., Martinez, H., Garrett, G. S., Neufeld, L. M., & de-Regil, L. M. (2021). Large-scale food fortification and biofortification in low- and middle-income countries: A review of programs, trends, challenges, and evidence gaps. Food and Nutrition Bulletin, 42(1), 3–24. https://doi.org/10.1177/0379572121991455
- Luthringer, C. L., Rowe, L. A., Vossenaar, M., & Garrett, G. S. (2015). Regulatory monitoring of fortified foods: Identifying barriers and good practices. Global Health: Science and Practice, 3(3), 446–461. https://doi.org/10.9745/GHSP-D-15-00171
- Sayed, A. R., Bourne, D., Pattinson, R., Nixon, J., & Henderson, B. (2008). Decline in the prevalence of neural tube defects following folic acid fortification and its cost-benefit in South Africa. Birth Defects Research Part A: Clinical and Molecular Teratology, 82(4), 211–216. https://doi.org/10.1002/bdra.20442
- Pachón, H., Spohrer, R., Mei, Z., & Serdula, M. K. (2015). Evidence of the effectiveness of flour fortification programs on iron status and anemia: A systematic review. Nutrition Reviews, 73(11), 780–795. https://doi.org/10.1093/nutrit/nuv037
- Allen, L., de Benoist, B., Dary, O., & Hurrell, R. (2006). Guidelines on food fortification with micronutrients. Geneva: WHO/FAO.
- Horton, S., Mannar, V., & Wesley, A. (2008). Food fortification with iron and folic acid: Costs, benefits, and financing. Geneva: World Health Organization.
Micronutrient deficiencies (MNDs)—including iron-deficiency anemia, vitamin A deficiency, iodine deficiency
and zinc deficiency—continue to be a complex problem in Sub-Saharan Africa (SSA) that disproportionately burdens
women of childbearing age, infants and young children, as well as other vulnerable populations. The following three
consumer staples—universal salt iodization (USI), flour fortification, and edible oil fortification—and large-scale food
fortification (LSFF) have been recognized as cost-effective interventions. Despite such efforts however, progress has been
uneven, with gaps and weak enforcement of legal instruments, poor monitoring systems, unequal coverage and donor
dependency in financing minimizing the impact. There is progress, for example decreases in neural tube defects in South
Africa and improved iodine sufficiency in certain countries, but wider reductions in anemia and vitamin A deficiency remain
erratic. There is a strong equity dimension involved, notably because urban and wealthy groups benefit more than rural
and marginalized ones. New solutions — biofortification of staple crops, digital surveillance platforms and enhanced public-
-private collaborations -- hold the potential to address these gaps, but their long-term sustainability and integration with
other nutrition strategies need to be investigated. This scoping review assesses the evidence on the applicability, effective
coverage and policy implications of fortification in SSA while highlighting best practices for success, ongoing challenges and
research priorities to guide future nutrition policy and programming.
Keywords :
Micronutrient Deficiencies; Food Fortification; Equity; Sub-Saharan Africa; Anemia; Biofortification; Nutrition Policy; Public–Private Partnerships.