Mobile Health, Pharmacist-Led Interventions and Home Medication Management: A Comprehensive Review of the Literature


Authors : Mitanshu Modhia; Dr. Indermeet Singh Anand; Paridhi Vyas; Dr. Dhiren L. Chaudhary

Volume/Issue : Volume 11 - 2026, Issue 1 - January


Google Scholar : https://tinyurl.com/47paktz5

Scribd : https://tinyurl.com/583sk6b9

DOI : https://doi.org/10.38124/ijisrt/26jan1602

Note : A published paper may take 4-5 working days from the publication date to appear in PlumX Metrics, Semantic Scholar, and ResearchGate.


Abstract : Medication adherence remains a central determinant of treatment success in chronic diseases. In recent years, the integration of pharmacist-led services, home-based reviews and mobile health (mHealth) technologies has gained increasing attention as innovative mechanisms to improve adherence, quality of life (QOL) and clinical outcomes. This review synthesizes evidence from 17 studies spanning pharmacist interventions, mHealth applications, home medication reviews, telehealth strategies and caregiver-oriented digital learning. The findings show consistent short-term improvements in adherence and patient engagement across many digital and pharmacist-driven programs, however evidence on long-term clinical effectiveness, scalability and sustainability remains limited. Substantial gaps persist around user engagement, privacy concerns, contextual adaptability and healthcare provider integration. The review highlights the need for large, theory-driven and community-based trials to validate and optimize these evolving models of care.

Keywords : Medication Adherence, Pharmacist-Led Interventions, Mobile Health (mHealth), Home Medication Review, Digital Health, Chronic Disease Management, Quality of Life, Telehealth.

References :

  1. Kristin S. Alvarez, Denise L. Yeung, et. al, “Low-health literacy flashcards & mobile video reinforcement to improve medication adherence in patients on oral diabetes, heart failure, and hypertension medication.” PMC. 2018, 57(1), 30-37.
  2. Bruno Francaviglia, Luca Lombardo, Bianca Pellizzeri, Federica Agnello et. al, “Clinical feasibility of a quick response code-based digital self-reporting of medication adherence: results in patients on ticagrelor therapy from the APOLLO-QR observational study.” Eur Heart J Digit Health. 2025, 6(4), 733-741.
  3. Dilip Chandrasekhar, Hridya Mary Thomas, Elizabeth Joseph and Farzana Abdul Ghaffoor., “The role of pharmacist-led home medication review in a community setting and the preparation of a medication list.” Clin. Epidemiol. Glob. Health. 2019, 7(1), 66-70.
  4. Richard Holland, Elizabeth Lenaghan, Ian Harvey, Richard Smith, et al., “Does home-based medication review keeps older people out of hospital? The HOMER randomised controlled trial.” BMJ. 2005, 330, 293.
  5. Michele Monzon-Kenneke, Paul Chiang, Nengliang (Aaron) Yao and Mark Greg., “Pharmacist medication review: An integrated team approach to serve home-based primary care patients.” PLoS One. 2021, 16(5), e0252151.
  6. Sheikh Rubana Hossain, Akanksha N Samant, Briana C Balsamo, Chelsea E Hawley and Michael C Zanchelli., “Effect of Medication Management at Home via Pharmacist-Led Home Tele visits: Protocol for a Cluster Randomized Controlled Trial.” JMIR Res. Protoc. 2025, 14, e65141.
  7. Yogesh Gautam, AK Sharma1, AK Agarwal, MK Bhatnagar and Roochika Ranjan Trehan., “A Cross-sectional Study of QOL of Diabetic Patients at Tertiary Care Hospitals in Delhi.” Indian J Community Med. 2009, 34(4), 346-350.
  8. Muhammad Zahid Iqbal and Saad S. Alqahtani., “Effect of pharmacist led intervention on health-related quality of life in diabetic patients assessed using EQ5D domains and visual analogue scale.” Sci. Rep. 2025, 15, 21222.
  9. HyoRim Ju, EunKyo Kang, YoungIn Kim, HyunYoung Ko and Belong Cho., “The Effectiveness of a Mobile Health Care App and Human Coaching Program in Primary Care Clinics: Pilot Multicentered Real-World Study.” JMIR Mhealth Uhealth. 2022, 10(5), e34531.
  10. Dauster Souza Pereira and Priscilla Perez da Silva Pereira., “Self-directed learning of informal caregivers using mobile health: a systematic review.” BMC Health Serv. Res. 2025, 25, 911.
  11. Backes C, Moyano C, Rimaud C, Bienvenu C and Schneider MP., “Digital Medication Adherence Support: Could Healthcare Providers Recommend Mobile Health Apps?” Front. Med. Technol. 2021, 2, 616242.
  1. Christa E. Hartch, Mary S. Dietrich, B. Jeanette Lancaster, Deonni P. Stolldorf and Shelagh A. Mulvaney., “Effects of a medication adherence app among medically underserved adults with chronic illness: a randomized controlled trial.” J. Behav. Med. 2024, 47, 389-404.
  2. Yihang Peng, Han Wang, Qin Fang, Liling Xie, Lingzhi Shu, Wenjing Sun and Qin Liu., “Effectiveness of Mobile Applications on Medication Adherence in Adults with Chronic Diseases: A Systematic Review and Meta-Analysis.” JMCP. 2020, 26(4), 550-561.
  3. Shaza Gamal, Ahmad Mohamad Abbas Elseasi, Nirmeen Ahmed Sabry and Samar Farghali Farid., “Impact of pharmacist led mobile application on medication adherence and efficacy in chronic kidney disease.” NPJ Digit. Med. 2025, 8, 325.
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  5. Indra Gayatri Valliyappan, Hooi Min Lim, YewKong Lee and Chirk Jenn Ng., “Exploring primary care doctors’ perceptions and experiences in adopting mHealth with patients: A qualitative study.” Digital Health. 2025, 11, 1-9.
  6. Helmut Brath, Jurgen Morak, Thomas Kastenbauer, Robert Modre-Osprian et. al., “Mobile health (mHealth) based medication adherence measurement a pilot trial using electronic blisters in diabetes patients.” Br. J. Clin. Pharmacol. 2013, 76(1), 47-55.

Medication adherence remains a central determinant of treatment success in chronic diseases. In recent years, the integration of pharmacist-led services, home-based reviews and mobile health (mHealth) technologies has gained increasing attention as innovative mechanisms to improve adherence, quality of life (QOL) and clinical outcomes. This review synthesizes evidence from 17 studies spanning pharmacist interventions, mHealth applications, home medication reviews, telehealth strategies and caregiver-oriented digital learning. The findings show consistent short-term improvements in adherence and patient engagement across many digital and pharmacist-driven programs, however evidence on long-term clinical effectiveness, scalability and sustainability remains limited. Substantial gaps persist around user engagement, privacy concerns, contextual adaptability and healthcare provider integration. The review highlights the need for large, theory-driven and community-based trials to validate and optimize these evolving models of care.

Keywords : Medication Adherence, Pharmacist-Led Interventions, Mobile Health (mHealth), Home Medication Review, Digital Health, Chronic Disease Management, Quality of Life, Telehealth.

Paper Submission Last Date
28 - February - 2026

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