Authors : Aaska Patel; Aayushi Bhavasar; Brinda Joshi; Maitri Parmar; Jhanvi Kapatel

Volume/Issue : Volume 10 - 2025, Issue 2 - February

Google Scholar : https://tinyurl.com/3mzyckv6

Scribd : https://tinyurl.com/2w8pskbf

DOI : https://doi.org/10.5281/zenodo.14959451

Abstract : A 21-year-old female with severe acne developed exfoliative dermatitis after applying a cream containing mometasone furoate (0.025%), hydroquinone (2%), and tretinoin (0.025%) at night. Within a day, she experienced redness and skin peeling, which was classified as a probable adverse drug reaction (ADR) based on Naranjo’s, WHO-UMC, and Karch & Lasagna causality scales. The reaction was assessed as moderate, predictable, and preventable. Management included discontinuation of all medications and treatment with Prednisone 10 mg (1-0-1), Nevlon Cream (1-1-1) mixed with Fucibet Cream, and sunlight avoidance. This case highlights the risks associated with inappropriate corticosteroid and retinoid use in acne treatment and the importance of proper patient counselling.

References :

1. Emphasis on Exfoliative Dermatitis: The Epidemiology and Therapeutic Perspectives [Internet]. Walsh Medical Media; [cited 2025 Feb 10]. Available from:https://www.walshmedicalmedia.com/open-access/emphasis-on-exfoliative-dermatitis- the-epidemiology-and-therapeutic-perspectives-123575.html
2. Clinico-etiological study of exfoliative dermatitis: A case series [Internet]. International Archives of Biomedical and Clinical Research; [cited 2025 Feb 10]. Available from: https://iabcr.org/index.php/iabcr/article/view/649