Authors : Dr. Nandan Kishur Kar; Dr. Manash Chakraborty; Dr. Srayoshi Barua; Dr. Sujan Kumar Dey

Volume/Issue : Volume 11 - 2026, Issue 3 - March

Google Scholar : https://tinyurl.com/8snnse6m

Scribd : https://tinyurl.com/49e6es5a

DOI : https://doi.org/10.38124/ijisrt/26mar1414

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Abstract : Sexual dysfunction is a multifactorial condition that reflects underlying neuroendocrine disturbances as well as psychosocial difficulty. We are presenting a case report of a 28-year-old bisexual male with concurrent acquired Hypoactive Sexual Desire Disorder (HSDD) with Premature Ejaculation (PE) and Erectile Dysfunction (ED). Endocrine evaluation revealed Hypogonadotropic Hypogonadism, Hyperprolactinaemia, and Subclinical Hypothyroidism, indicating a significant suppression of Hypothalamic-Pituitary-Gonadal (HPG) axis, which is further, worsened by psychosocial stressors, including minority stress, self-devaluation, childhood sexual abuse, and dyadic conflict following marriage. A multidisciplinary approach including Testosterone replacement, Dopamine agonist therapy, Thyroid hormone replacement, Dopaminergic antidepressant, Behavioral therapy, and Couple therapy led to in progressive improvement with restoration of sexual function and interpersonal equilibrium. This case emphasizes the importance of integrating hormonal, psychological, and socio-cultural factors in the diagnosis and management of male sexual dysfunction, especially in sexual minority populations.

Keywords : Hypoactive Sexual Desire Disorder, Bisexual Male, Premature Ejaculation, Erectile Dysfunction, Hypogonadotropic Hypogonadism, Hyperprolactinaemia, Behavioural Therapy, Couple Therapy

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