Authors : Dr. Abreen; Dr. Imran Hussain; Dr. Suman Kumar Singh; Dr. Nirmala Rai; Puja Kumari

Volume/Issue : Volume 11 - 2026, Issue 8 - August

---

Google Scholar : https://tinyurl.com/3scbxp9f

Scribd : https://tinyurl.com/bdcvbf25

DOI : https://doi.org/10.38124/ijisrt/26aug652

Note : A published paper may take 4-5 working days from the publication date to appear in PlumX Metrics, Semantic Scholar, and ResearchGate.

---

Abstract : Background: Photographs and overall impressions dominate many evaluations of minimally invasive facial procedures. However, facial symmetry, skin biomechanics, recovery, and patient-reported benefits are all separate outcome domains. This study aimed to combine objective and subjective outcome measures and their predictors for the first time, over 12 weeks. 150 adult patients were divided into 6 groups, each undergoing 1 of 6 selected minimally invasive facial procedures. Symmetry, skin elasticity, hydration, firmness, and wrinkles were assessed for each group, pre- and post- procedures, at 2, 6, and 12 weeks. A number of statistical analyses were conducted.

Keywords : Facial Symmetry, Skin Biomechanics, Minimally Invasive Procedures, Patient-Reported Outcomes, Elasticity, Aesthetic Medicine.

References :

1. Al-Dhubaibi, M. S., Mohammed, G. F., Atef, L. M., Bahaj, S. S., Al-Dhubaibi, A. M., & Bukhari, A. M. (2025). Artificial intelligence in aesthetic medicine: Applications, challenges, and future directions. Journal of Cosmetic Dermatology, 24(6), e70241. https://doi.org/10.1111/jocd.70241
2. Al-Taie, D. S., AlEdani, E. M., Gurramkonda, J., et al. (2023). Non-surgical rhinoplasty: A systematic review of its techniques, outcomes, and patient satisfaction. Cureus, 15(12), e50728. https://doi.org/10.7759/cureus.50728
3. Bravo, B. S. F., Calvacante, T., Zafra, M. C., Elias, M. C., Bravo, L. G., & Nobre, C. S. (2025). Exploring the safety and satisfaction of patients injected with collagen biostimulators: A prospective investigation into injectable poly-L-lactic acid. Journal of Cosmetic Dermatology, 24(2), e16723. https://doi.org/10.1111/jocd.16723
4. Foppiani, J. A., Fanning, J. E., Beltran, K., et al. (2025). Microneedling for facial rejuvenation: A systematic review. Aesthetic Plastic Surgery, 49(17), 4949-4960. https://doi.org/10.1007/s00266-025-04972-z
5. Lee, J. H., Kim, J., Lee, Y. N., Choi, S., Lee, Y. I., Suk, J., & Lee, J. H. (2024). The efficacy of intradermal hyaluronic acid filler as a skin quality booster: A prospective, single-center, single-arm pilot study. Journal of Cosmetic Dermatology, 23(2), 409-416. https://doi.org/10.1111/jocd.15944
6. Meçani, R., et al. (2025). Combined and hybrid treatments of hyaluronic acid and calcium hydroxylapatite: A systematic review. Aesthetic Plastic Surgery. https://doi.org/10.1007/s00266-025-04904-x
7. Muizzuddin, N., & Benjamin, R. (2022). Beauty from within: Oral administration of methylsulfonylmethane improves signs of skin ageing. International Journal for Vitamin and Nutrition Research, 92(3-4), 182-191. https://doi.org/10.1024/0300-9831/a000643
8. Park, G. H., Kwon, H. H., Seok, J., Yang, S. H., Lee, J., Shin, E., et al. (2023). Efficacy of combined treatment with human adipose tissue stem cell-derived exosome-containing solution and microneedling for facial skin aging: A 12-week randomized split-face study. Journal of Cosmetic Dermatology, 22(12), 3418-3426. https://doi.org/10.1111/jocd.15872
9. Pooth, R., Sattler, S., Westerberg, F., Pavicic, T., & Kerscher, M. (2025). Transforming skin quality evaluation with AI: From subjective grading to data-driven precision. Journal of Cosmetic Dermatology, 24(S4), e70371. https://doi.org/10.1111/jocd.70371
10. Triana, L., Palacios Huatuco, R. M., Campiglio, G., & Liscano, E. (2024). Trends in surgical and nonsurgical aesthetic procedures: A 14-year analysis of the International Society of Aesthetic Plastic Surgery statistics. Aesthetic Plastic Surgery, 48(20), 4217-4227. https://doi.org/10.1007/s00266-024-04260-2
11. Umeda, M., Tamura, T., Okumura, K., Kiuchi, R., & Teranishi, H. (2025). Objective evaluation of platelet-rich plasma mesotherapy on facial skin quality: An interim split-face analysis using an advanced imaging system. Regenerative Therapy, 30, 969-976. https://doi.org/10.1016/j.reth.2025.10.008
12. World Medical Association. World Medical Association Declaration of Helsinki: Ethical Principles for Medical Research Involving Human Subjects. JAMA. 2013;310(20):2191–2194. doi:10.1001/jama.2013.281053.
13. International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use. Integrated Addendum to ICH E6(R1): Guideline for Good Clinical Practice E6(R2). Geneva: International Council for Harmonisation; 2016.