Nature's Arsenal Against Alzheimer's: A Comprehensive Review of Herbal Remedies and their Therapeutic Potential


Authors : Jayesh H. Lahoti; A.M. Wankhade; V.V .Paithankar; J.V. Vyas

Volume/Issue : Volume 9 - 2024, Issue 1 - January

Google Scholar : http://tinyurl.com/466yvjsd

Scribd : http://tinyurl.com/4dy9m3e2

DOI : https://doi.org/10.5281/zenodo.10574875

Abstract : Extracellular amyloid-beta (Aβ) plaques and intracellular accumulation of neurofibrillary tangles are indicative of the prevalence of Alzheimer's disease (AD), a neurological illness that impairs memory and learning. It is now imperative to find new therapeutic medicines with more efficacy and fewer adverse effects due to the aging population and rising incidence of AD. Conventionally, a range of synthetic drugs are used to treat symptoms and prevent the advancement of the condition. These drugs include tacrine, donepezil, galantamine, rivastigmine, memantine, glutathione, ascorbic acid, ubiquinone, ibuprofen, and ladostigil .The spotlight has shifted to herbal medicines due to their perceived effectiveness and minimal side effects. Due to their potential to alleviate symptoms associated with neurological illnesses, Lavandula angustifolia, Ginkgo biloba, Melissa officinalis, Crocus sativus, ginseng, Salvia miltiorrhiza, and Magnolia officinalis have become more well-known. This article provides an overview of the therapeutic effects of these phytomedicines, showcasing their impact on various factors related with Alzheimer’s.

Keywords : Alzheimer, Traditional use, Phytochemistry, Pharmacology, Therapeutic.

Extracellular amyloid-beta (Aβ) plaques and intracellular accumulation of neurofibrillary tangles are indicative of the prevalence of Alzheimer's disease (AD), a neurological illness that impairs memory and learning. It is now imperative to find new therapeutic medicines with more efficacy and fewer adverse effects due to the aging population and rising incidence of AD. Conventionally, a range of synthetic drugs are used to treat symptoms and prevent the advancement of the condition. These drugs include tacrine, donepezil, galantamine, rivastigmine, memantine, glutathione, ascorbic acid, ubiquinone, ibuprofen, and ladostigil .The spotlight has shifted to herbal medicines due to their perceived effectiveness and minimal side effects. Due to their potential to alleviate symptoms associated with neurological illnesses, Lavandula angustifolia, Ginkgo biloba, Melissa officinalis, Crocus sativus, ginseng, Salvia miltiorrhiza, and Magnolia officinalis have become more well-known. This article provides an overview of the therapeutic effects of these phytomedicines, showcasing their impact on various factors related with Alzheimer’s.

Keywords : Alzheimer, Traditional use, Phytochemistry, Pharmacology, Therapeutic.

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