Authors : Made Aditya Artha Nugraha

Volume/Issue : Volume 9 - 2024, Issue 6 - June

Google Scholar : https://tinyurl.com/bat2ypf8

Scribd : https://tinyurl.com/bdd9y36r

DOI : https://doi.org/10.38124/ijisrt/IJISRT24JUN1007

Note : A published paper may take 4-5 working days from the publication date to appear in PlumX Metrics, Semantic Scholar, and ResearchGate.

Abstract : The pathophysiology of stroke is a complicated process, and it is thought that neuronal damage is caused by oxidative stress and inflammatory responses. Acute ischemic stroke (AIS)'s pathophysiology relies heavily on the inflammatory response. Raised degrees of fiery markers like C-receptive protein (CRP) and interleukin- 6 are related with unfortunate visualization in ischemic stroke. Prostaglandin E2, which stimulates the hypothalamus and raises body temperature, can be released into the brain by interleukin-6. IL-6 articulation in intense stroke still up in the air by infarct size yet additionally under hereditary control. The instrument of IL-6's impact on post-stroke discernment stays unexplained. After a stroke, the chronic inflammatory response may start neurotoxic pathways that cause progressive degeneration. Chemokines, activation of microglia and astrocytes, and neuroinflammation- mediated disorders may also be exacerbated by damaged neurons.

Keywords : Stroke, Interleukin-6, Prognosis.

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