Authors :
Dr. Devyani Khorate; Dr. Suvarna Pai; Dr. Pritam Bhatmare
Volume/Issue :
Volume 10 - 2025, Issue 3 - March
Google Scholar :
https://tinyurl.com/yvr4hh2t
Scribd :
https://tinyurl.com/3h8kfbp8
DOI :
https://doi.org/10.38124/ijisrt/25mar064
Note : A published paper may take 4-5 working days from the publication date to appear in PlumX Metrics, Semantic Scholar, and ResearchGate.
Abstract :
A 76-year-old male patient presented with a 4-5 day history of urinary tract infection symptoms and two days of
hematuria with clot formation. The patient was treated briefly with transfusions at an outside hospital. He is a known
diabetic and hypertensive for 20 years, had a cerebrovascular accident 9 years ago, and had multiple hospitalizations and
transfusions due to undiagnosed persistent thrombocytopenia and anemia for 3 to 4 years. General physical examination is
unremarkable. Routine lab tests, Urine microscopy and culture, Ultrasonography and Bone marrow examination (BMA)
were performed. The BMA and biopsy revealed Normomegaloblastic hypercellular marrow with trilineage dysplasia,
suggestive of Myelodysplastic syndrome (MDS). MDS cytogenetics (FISH) was positive for Monosomy 7. Despite
comprehensive supportive management, the patient’s clinical condition progressively worsened.
Keywords :
MDS , Monosomy 7, Urinary Bladder Hematoma.
References :
- Garcia-Manero G. Myelodysplastic syndromes: 2023 update on diagnosis, risk-stratification, and management. Am J Hematol. 2023;98(8):1307-1325.
- Li H, Hu F, Gale RP, Sekeres MA, Liang Y. Myelodysplastic syndromes. J Clin Oncol. 2021;39(16):1751-1761.
- Hellström-Lindberg E, et al. Myelodysplastic syndromes: moving towards personalized management. Lancet Haematol. 2018;5(12):666-679
A 76-year-old male patient presented with a 4-5 day history of urinary tract infection symptoms and two days of
hematuria with clot formation. The patient was treated briefly with transfusions at an outside hospital. He is a known
diabetic and hypertensive for 20 years, had a cerebrovascular accident 9 years ago, and had multiple hospitalizations and
transfusions due to undiagnosed persistent thrombocytopenia and anemia for 3 to 4 years. General physical examination is
unremarkable. Routine lab tests, Urine microscopy and culture, Ultrasonography and Bone marrow examination (BMA)
were performed. The BMA and biopsy revealed Normomegaloblastic hypercellular marrow with trilineage dysplasia,
suggestive of Myelodysplastic syndrome (MDS). MDS cytogenetics (FISH) was positive for Monosomy 7. Despite
comprehensive supportive management, the patient’s clinical condition progressively worsened.
Keywords :
MDS , Monosomy 7, Urinary Bladder Hematoma.
