Authors :
Dr. Snehal Ashokkumar Sonewane; Dr. Uday S. Mohite; Dr. Vivek S. Gosavi; Dr. Mayur Kulkarni
Volume/Issue :
Volume 9 - 2024, Issue 6 - June
Google Scholar :
https://tinyurl.com/4cysd4wt
Scribd :
https://tinyurl.com/986xf3ra
DOI :
https://doi.org/10.38124/ijisrt/IJISRT24JUN1354
Note : A published paper may take 4-5 working days from the publication date to appear in PlumX Metrics, Semantic Scholar, and ResearchGate.
Abstract :
Purpose:
To evaluate the prevalence and clinical characteristics
of dry eye disease (DED) among individuals with type 2
diabetes in a community-based setting. Additionally, the
study aimed to identify factors associated with the
presence of DED in this population.
Methods:
A total of 136 randomly selected patients diagnosed
with type 2 diabetes participated in the study, undergoing
comprehensive ophthalmic evaluations. These evaluations
included corneal sensitivity testing, tear film break-up time
(BUT) assessment, the Schirmer I test, and fundus
photography. The severity of diabetic retinopathy (DR)
was graded according to the International Severity Scale.
Results:
Among the 136 subjects, 23 (17.1%) were diagnosed
with DED. There were significant associations between
DED and higher blood glucose levels (P < 0.001) as well as
elevated glycosylated hemoglobin (HbA1c) levels (P <
0.001).
Conclusions:
These findings highlight the importance of
incorporating dry eye assessments into the routine
screening protocol for diabetic patients. The observed
prevalence of DED at 17.1% in this cohort is lower than
the rates reported in other studies. Importantly,
individuals with diabetes who have poorer metabolic
control are at a higher risk of developing DED.
Keywords :
Dry Eye Disease, Type 2 Diabetic Patients, Glycosylated Hemoglobin.
References :
- Pradeepa R, Mohan V. Epidemiology of type 2 diabetes in India. Indian J Ophthalmol. 2021;69(12):2932-2938.
- Verma R. National programme on prevention and control of diabetes in India: Need to focus. Australas Med J. 2012 Jul 1;5(6):310–315.
- Sayin N, Kara N, Pekel G. Ocular complications of diabetes mellitus. World J Diabetes. 2015 Feb 15;6(1):92-108.
- Zou X, Lu L, Xu Y, Zhu J, He J, Zhang B, et al. Prevalence and clinical characteristics of dry eye disease in community-based type 2 diabetic patients: The Beixinjing Eye Study. BMC Ophthalmol. 2018 May 24;18:117.
- Van Tilborg MM, Murphy PJ, Evans KS. Impact of dry eye symptoms and daily activities in a modern office. Optom Vis Sci. 2017 Jun;94(6):688-693.
- Yazdani Ibn Taz MK, Han MM, Jonuscheit S, Collier A, Nally JE, Hagan S. Patient-reported severity of dry eye and quality of life in diabetes. Clin Ophthalmol. 2019 Jan 25;13:217-224.
- Shaikh DD, Imdad T, Ali S, Ali F, Shaikh SP, Surhio WA, et al. Prevalence of dry eye disease in type 2 diabetic patients and its association with diabetic retinopathy. Pak J Med Health Sci. 2021 Nov;15(11):3269-3272.
- Goebbels M. Tear secretion and tear film function in insulin-dependent diabetics. Br J Ophthalmol. 2000 Jan;84(1):19-21.
- Sarkar KC, Bhattacharyya S, Sarkar P, Maitra A, Manda RK. An observational study on the prevalence of dry eyes in type 2 diabetes mellitus patients and its relation to the duration and severity of disease. J Clin Diagn Res. 2018 Jan;12(1):NC01-NC04.
- Zhang X, Zhao L, Deng S, Sun X, Wang N. Dry eye syndrome in patients with diabetes mellitus: prevalence, etiology, and clinical characteristics. J Ophthalmol. 2016;2016:8201053.
- Hasan IN, Aggarwal P, Gurav A, Patel N. Assessment of dry eye status in type 2 diabetic patients in tertiary health care hospital, India. Int Organ Sci Res J Dent Med Sci. 2014;13:6-11.
- Moss SE, Klein R, Klein BE. Prevalence of and risk factors for dry eye syndrome. Arch Ophthalmol. 2000 Sep;118(9):1264-1268.
- Nepp J, Abela C, Polzer I, Derbolav A, Wedrich A. Is there a correlation between the severity of diabetic retinopathy and keratoconjunctivitis sicca? Cornea. 2000 Jul;19(4):487-491.
- Seifart U, Strempel I. The dry eye and diabetes mellitus. Ophthalmologe. 1994 Jul;91(4):235-239.
- Kaiserman I, Kaiserman N, Nakar S, Vinker S. Dry eye in diabetic patients. Am J Ophthalmol. 2005 Apr;139(4):498-503.
- Schultz RO, Van Horn DL, Peters MA, Klewin KM, Schutten WH. Diabetic keratopathy. Trans Am Ophthalmol Soc. 1981;79:180-199.
- Ranjan R, Shukla SK, Veer Singh C, Mishra BN, Sinha S, Sharma BD. Prevalence of dry eye and its association with various risk factors in rural setup of western Uttar Pradesh in a tertiary care hospital. Open J Prev Med. 2016 Feb;6(1):57-63.
- Lévêque P-M, Zéboulon P, Brasnu E, Baudouin C, Labbé A. Optic disc vascularization in glaucoma: value of spectral-domain optical coherence tomography angiography. J Ophthalmol. 2016;2016:1-7.
- Ozawa GY, Bearse MA, Adams AJ. Male-female differences in diabetic retinopathy? Curr Eye Res. 2015 Feb;40(2):234-246.
- Burda N, Mema V, Mahmudi E, Selimi B, Zhugli S, Lenajni B, et al. Prevalence of dry eye syndrome in patients with type 2 diabetes mellitus. J Acute Dis. 2013;2(1):48-51.
- Najafi L, Malek M, Valojerdi AE, Aghili R, Khamseh ME, Fallah AE, et al. Dry eye and its correlation to diabetes microvascular complications in people with type 2 diabetes mellitus. J Diabetes Complications. 2013 Sep;27(5):459-462.
Purpose:
To evaluate the prevalence and clinical characteristics
of dry eye disease (DED) among individuals with type 2
diabetes in a community-based setting. Additionally, the
study aimed to identify factors associated with the
presence of DED in this population.
Methods:
A total of 136 randomly selected patients diagnosed
with type 2 diabetes participated in the study, undergoing
comprehensive ophthalmic evaluations. These evaluations
included corneal sensitivity testing, tear film break-up time
(BUT) assessment, the Schirmer I test, and fundus
photography. The severity of diabetic retinopathy (DR)
was graded according to the International Severity Scale.
Results:
Among the 136 subjects, 23 (17.1%) were diagnosed
with DED. There were significant associations between
DED and higher blood glucose levels (P < 0.001) as well as
elevated glycosylated hemoglobin (HbA1c) levels (P <
0.001).
Conclusions:
These findings highlight the importance of
incorporating dry eye assessments into the routine
screening protocol for diabetic patients. The observed
prevalence of DED at 17.1% in this cohort is lower than
the rates reported in other studies. Importantly,
individuals with diabetes who have poorer metabolic
control are at a higher risk of developing DED.
Keywords :
Dry Eye Disease, Type 2 Diabetic Patients, Glycosylated Hemoglobin.