Authors : Dr. Shaik Saifur Rehman; Dr. Mohammed Ahsan Faroqui; Dr. M. A. Lateef Siddiqui; Dr. N. M. Sarfaraz Nawaz; Dr. Sharik Imran Abdul Rafique

Volume/Issue : Volume 10 - 2025, Issue 7 - July

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DOI : https://doi.org/10.38124/ijisrt/25jul1338

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Abstract : Oligospermia and spermatorrhea are two significant yet distinct disorders of the male reproductive system, frequently encountered in both modern urology and traditional Unani medicine. Oligospermia refers to a low sperm count, which is a direct cause of male infertility. In contrast, spermatorrhea involves the involuntary discharge of semen without orgasm, which, although not always linked directly to infertility, reflects deeper neuromuscular or psychological imbalances. This review discusses the pathophysiology, clinical presentation, diagnostic criteria, and treatment strategies for both conditions with a focus on the traditional Unani system. Emphasis is laid on the temperament-based (mizaji) approach of Unani Tibb and its integration with modern medical understandings.

References :

1. World Health Organization. WHO Laboratory Manual for the Examination and Processing of Human Semen. 6th ed. Geneva: WHO Press; 2021.
2. World Health Organization. WHO laboratory manual for the examination and processing of human semen. 5th ed. Geneva: WHO; 2010.
3. Wang, H., & Qin, F. (2011). Clinical observations on treatment of spermatorrhea and nocturnal emission with acupuncture. Journal of Traditional Chinese Medicine, 31(3), 213-216.
4. Central Council for Research in Unani Medicine (CCRUM). Standard Unani Medical Terminology. New Delhi: Ministry of AYUSH, Govt. of India; 2012. p. 220–231. ([CCRUM PDF]—Section on morbid mizāj types).
5. Choy JT, Eisenberg ML. Male infertility: A clinical review. F1000Res. 2018;7:F1000 Faculty Rev-190. doi:10.12688/f1000research.13103.1. PMID: 29568406; PMCID: PMC5840380.
6. Abid M, Naaz F, Khan N. Clinical evaluation of Mizāj in Qillat-e-Huwain-e-Manvia (Oligozoospermia). World Journal of Pharmacy and Pharmaceutical Sciences. 2016;5(7):1261–1270.
7. Nifras MMM, Farooqui MA, Muthalib AM.Unani perspective of Qillat-e-Mani (Oligospermia): A review. Int J Creat Res Thoughts. 2021;9(5):b651–b657.
8. Bynum B. Spermatorrhoea. Lancet. 2001 Mar 3;357(9257):726.
9. Kabiruddin M. Moalijat Sharah Asbab (Tarjuma‑e‑Kabir). Vol. 1. Hyderabad: Hikmat Book Depot; c1916. p. 195–6.
10. Osman P, Hussain MM, Zahoor S, Saffura S, Tasleem A, Anjum F, Begum K. A comprehensive review on the efficacy of Sufoof-e‑Tukhme Tamarhindi (Tamarindus indicus) in the management of Jiryan‑e‑Mani (Spermatorrhea). Int J Innov Sci Res Technol. 2025;10(1):1748–51.
11. Yahya WA‑M, Yahya RA‑M, Azab EA, Shkal KM. Insights into Varicocele: Anatomical considerations, prevalence, incidence, etiology, pathophysiology of infertility with varicocele, diagnosis, and management. Clinical Reviews and Case Reports. 2025;4(2):[e‑pub ahead of print]. doi:10.31579/2835‑7957/137.
12. Carroll M. Disorders of male reproductive endocrinology. In: Clinical Reproductive Science. Cambridge: Academic Press; 2018. p. 109–124.
13. Henkel R. Infection in infertility. In: Parekattil SJ, Agarwal A, editors. Male Infertility: Contemporary Clinical Approaches, Andrology, ART and Antioxidants. Cham: Springer; 2020. p. 409–424.
14. Dohle G. Obstructions of the male reproductive tract: diagnosis and management. In: Parekattil SJ, Agarwal A, editors. Male Infertility: Contemporary Clinical Approaches, Andrology, ART and Antioxidants. Cham: Springer; 2020. p. 425–438.
15. Parvez KF, Hussain SS. The role of industrial chemicals and occupational hazards in male infertility: a comprehensive review. Metall Mater Eng. 2025;31(1):52–65.
16. Paulis G. Chromosomic causes of infertility. In: Cavallini G, Beretta G, editors. Clinical Management of Male Infertility. Milan: Springer; 2014. p. 63–77.
17. Rehman SS, Faroqui MA, Siddiqui MAL, Nawaz NMS, Siddiqua A. Holistic understanding of oligospermia (Qillat-e-Mani) through Unani medicine: causes, diagnosis, and management strategies. Int J Novel Res Dev. 2025 Jul;10(7):b634–b639.
18. Agarwal A, Virk G, Ong C, du Plessis SS. Oxidative stress in male infertility: a systematic review of literature. Reprod Biomed Online. 2014;29(1):32–48. doi:10.1016/j.rbmo.2014.03.012.
19. Darby R. Pathologizing male sexuality: Lallemand, spermatorrhea, and the rise of circumcision. J Hist Med Allied Sci. 2005;60(3):283–319. doi:10.1093/jhmas/jri029.
20. Dimitriadis F, Karakitsios K, Tsounapi P, Tsambalas S, Loutradis D, Kanakas N, et al. Erectile function and male reproduction in men with spinal cord injury: a review. Andrologia. 2013;45(2):73–85. doi:10.1111/j.1439-0272.2012.01319.x
21. Rusz A, Pilatz A, Wagenlehner F, Linn T, Diemer TH, Schuppe HC, Lohmeyer J, Hossain H, Weidner W. Influence of urogenital infections and inflammation on semen quality and male fertility. World J Urol. 2012 Aug;30(1):23–30. doi:10.1007/s00345-011-0741-y. PMID: 22130694.
22. Beeder LA, Samplaski MK. Effect of antidepressant medications on semen parameters and male fertility. Int J Urol. 2020;27(1):39–46. doi:10.1111/iju.14087.
23. Kabeeruddin H. Sharh Asbab. Delhi: Idara Kitab-us-Shifa; p. 94–95.
24. Ibn Sina. Al-Qanun fi al-Tibb (The Canon of Medicine). Vol. 2. New Delhi: Idara Kitab-us-Shifa; 2007. p. 306–310.
25. Vella-Zarb RA, Cohen JN, McCabe RE, Rowa K. Differentiating sexual thoughts in obsessive-compulsive disorder from paraphilias and nonparaphilic sexual disorders. J Sex Marital Ther. 2015;41(2):148–162.