Oral Lichen Planus - An Enigma with Limited Treatment Options


Authors : Dr. M. Deivanayagi , Dr. Mammootty I. K

Volume/Issue : Volume 3 - 2018, Issue 1 - January


Google Scholar : https://goo.gl/DF9R4u

Scribd : https://goo.gl/8iSLpp

Thomson Reuters ResearcherID : https://goo.gl/3bkzwv


Abstract : Oral Lichen Planus (OLP) is a chronic inflammatory, T-cell-mediated autoimmune oral mucosal disease with unclear etiology. The clinical management of OLP poses considerable difficulties to the oral physician. A proper understanding of the pathogenesis, clinical presentation, diagnosis of the disease becomes important for providing the right treatment.All therapies are palliative, and none is effective universally. Currently employed treatment modalities include corticosteroids administered topically, intralesionally, or systemically. Alternative therapies include topical and systemic retinoids, griseofulvin, Cyclosporine, and surgery. Other medical treatments and experimental modalities, including mouth PUVA, have been reported to be effective. In this review, we discuss the various current treatment modalities of OLP.

Oral Lichen Planus (OLP) is a chronic inflammatory, T-cell-mediated autoimmune oral mucosal disease with unclear etiology. The clinical management of OLP poses considerable difficulties to the oral physician. A proper understanding of the pathogenesis, clinical presentation, diagnosis of the disease becomes important for providing the right treatment.All therapies are palliative, and none is effective universally. Currently employed treatment modalities include corticosteroids administered topically, intralesionally, or systemically. Alternative therapies include topical and systemic retinoids, griseofulvin, Cyclosporine, and surgery. Other medical treatments and experimental modalities, including mouth PUVA, have been reported to be effective. In this review, we discuss the various current treatment modalities of OLP.

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