Authors :
Abeywickrama S. N.; Tharshanan K.; Perera D. L. G.
Volume/Issue :
Volume 11 - 2026, Issue 9 - September
Google Scholar :
https://tinyurl.com/4kfeeprr
DOI :
https://doi.org/10.38124/ijisrt/26sep168
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working days from the publication date to appear in PlumX Metrics, Semantic Scholar, and
ResearchGate.
Abstract :
Background:
Antimicrobial resistance (AMR) is a leading global health threat, and rational antimicrobial use at the primary and
secondary healthcare level is central to Sri Lanka's National Action Plan for combating AMR. Facility-level data describing
how antimicrobials are actually used, benchmarked against the World Health Organization (WHO) Access, Watch, Reserve
(AWaRe) classification, remain scarce for secondary-care hospitals in Sri Lanka.
Objectives:
To describe the monthly pattern of antimicrobial dispensing at the outpatient department (OPD) of Base Hospital
Karawanella during 2025 and to classify consumption according to the WHO AWaRe framework.
Methods:
This was a retrospective, descriptive drug utilisation study using the OPD pharmacy's “countable drugs” dispensing
register for January-December 2025 (14 antimicrobial agents in 26 formulations). Each antimicrobial was classified by
WHO AWaRe category and by pharmacological class and route of administration. Descriptive statistics summarised total
and monthly dispensing volume, proportional AWaRe distribution, and the ranking of agents by volume.
Keywords :
Antimicrobial Resistance; AWaRe Classification; Antimicrobial Utilisation; Drug Utilisation Review; Antimicrobial Stewardship; Sri Lanka; Outpatient Prescribing.
References :
- Antimicrobial Resistance Collaborators. Global burden of bacterial antimicrobial resistance in 2019: a systematic analysis. Lancet. 2022;399(10325):629-655.
- World Health Organization. Global Action Plan on Antimicrobial Resistance. Geneva: World Health Organization; 2015.
- World Health Organization. AWaRe classification of antibiotics for evaluation and monitoring of use, 2023. Geneva: World Health Organization; 2023. (WHO/MHP/HPS/EML/2023.04). Available from: https://www.who.int/publications/i/item/WHO-MHP-HPS-EML-2023.04
- Zanichelli V, Sharland M, Cappello B, Moja L, Getahun H, Pessoa-Silva C, Sati H, van Weezenbeek C, Balkhy H, Simão M, Gandra S, Huttner B. The WHO AWaRe (Access, Watch, Reserve) antibiotic book and prevention of antimicrobial resistance. Bull World Health Organ. 2023;101(4):290-296.
- Elshenawy RA, Umaru N, Aslanpour Z. WHO AWaRe classification for antibiotic stewardship: tackling antimicrobial resistance - a descriptive study from an English NHS Foundation Trust prior to and during the COVID-19 pandemic. Front Microbiol. 2023;14:1298858.
- Ministry of Health, Sri Lanka. National Strategic Plan for Combating Antimicrobial Resistance in Sri Lanka 2017-2022. Colombo: Ministry of Health; 2017.
- Sri Lanka College of Microbiologists. National Strategic Plan for Combating Antimicrobial Resistance in Sri Lanka: end-term review of NSP-AMR 2017-2022 and development of NSP/NAP-AMR 2023-2028 [Internet]. 2023. Available from: https://slmicrobiology.lk/2023/07/28/national-strategic-plan-for-combating-antimicrobial-resistance-in-sri-lanka/
- World Health Organization. Sri Lanka: National Strategic Plan for Combating Antimicrobial Resistance 2023-2028 [Internet]. Geneva: World Health Organization; 2023. Available from: https://www.who.int/publications/m/item/sri-lanka-national-strategic-plan-for-combating-antimicrobial-resistance-2023-2028
- Sri Lanka College of Microbiologists. National Antimicrobial Resistance Surveillance System in Sri Lanka [Internet]. 2024. Available from: https://slmicrobiology.lk/2024/05/29/national-antimicrobial-resistance-surveillance-system-in-sri-lanka/
- Microbiology Society. Significant gaps in practice present despite higher level of public awareness in antibiotic use and antimicrobial resistance in the Western Province of Sri Lanka. Access Microbiol. 2025.
- Ministry of Health, Sri Lanka. National Medicinal Drug Policy for Sri Lanka. Colombo: Ministry of Health, in collaboration with the World Health Organization.
- Sri Lanka College of Microbiologists. Antibiotic guidelines [Internet]. Available from: https://slmicrobiology.lk/activities/college-activities/
- Zawahir S, Lekamwasam S, Aslani P. Antibiotic dispensing practice in Sri Lankan community pharmacies: a simulated client study. Res Social Adm Pharm. 2019;15(9):1158-1170.
- Divisional Secretariat, Ruwanwella. Hospitals - Divisional Secretariat, Ruwanwella [Internet]. Available from: http://www.ruwanwella.ds.gov.lk/index.php/en/hospitals.html
- World Health Organization. The WHO AWaRe (Access, Watch, Reserve) Antibiotic Book. Geneva: World Health Organization; 2022.
- Ariyawansa S, Gunawardana KN, Hapudeniya MM, Manelgamage NJ, Karunarathne CR, Madalagama RP, Ubeyratne KH, Wickramasinghe D, Tun HM, Wu P, Lam TTY, Chan OSK. One Health Surveillance of Antimicrobial Use and Resistance: Challenges and Successes of Implementing Surveillance Programs in Sri Lanka. Antibiotics (Basel). 2023;12(3):446.
- Sri Ranganathan S, Wanigatunge C, Senadheera GPSG, Beneragama BVSH. A national survey of antibacterial consumption in Sri Lanka. PLoS One. 2021;16(9):e0257424.
- Perera YK, Chulasiri PU, Jayatilleke SK. Prevalence, phenotypes of beta lactamase and clinical response to empirical therapy of urinary tract infections caused by third generation cephalosporin resistant Enterobacteriaceae in a tertiary care hospital, Sri Lanka. Oral presentation, 14th International Symposium on Antimicrobial Agents and Resistance / Annual Conference of the Korean Society for Antimicrobial Therapy, 2024.
Background:
Antimicrobial resistance (AMR) is a leading global health threat, and rational antimicrobial use at the primary and
secondary healthcare level is central to Sri Lanka's National Action Plan for combating AMR. Facility-level data describing
how antimicrobials are actually used, benchmarked against the World Health Organization (WHO) Access, Watch, Reserve
(AWaRe) classification, remain scarce for secondary-care hospitals in Sri Lanka.
Objectives:
To describe the monthly pattern of antimicrobial dispensing at the outpatient department (OPD) of Base Hospital
Karawanella during 2025 and to classify consumption according to the WHO AWaRe framework.
Methods:
This was a retrospective, descriptive drug utilisation study using the OPD pharmacy's “countable drugs” dispensing
register for January-December 2025 (14 antimicrobial agents in 26 formulations). Each antimicrobial was classified by
WHO AWaRe category and by pharmacological class and route of administration. Descriptive statistics summarised total
and monthly dispensing volume, proportional AWaRe distribution, and the ranking of agents by volume.
Keywords :
Antimicrobial Resistance; AWaRe Classification; Antimicrobial Utilisation; Drug Utilisation Review; Antimicrobial Stewardship; Sri Lanka; Outpatient Prescribing.