Pattern of Persistent Liver Disorders in Children


Authors : Dr. Venugopal Reddy. I.; Dr. Bhaskar Shenoy; Dr. Dinesh Kumar Vuppu

Volume/Issue : Volume 8 - 2023, Issue 8 - August

Google Scholar : https://bit.ly/3TmGbDi

Scribd : https://tinyurl.com/y4aupdra

DOI : https://doi.org/10.5281/zenodo.8337491

Abstract : Introduction: Liver diseases significantly impact children's morbidity and mortality, with non-alcoholic fatty liver disease (NAFLD) becoming more prevalent. Geographical heterogeneity in etiology varies, with hepatitis virus being the primary cause in South East Asia. Biliary abnormalities like biliary atresia can manifest as chronic liver disease in children with cirrhosis and portal hypertension. In developing countries, metabolic illnesses causing chronic liver disease have not been thoroughly studied. Methods: Our hospital is a tertiary care facility in a large urban centre and serves as the referral centre. Cases admitted from August 2006 to August 2008 were analyzed and follow up was done. The dates of the onset of illness, fulfillment of diagnostic criteria, diagnosis and treatment all were noted.Conclusion: Chronic liver disease is suspected in children with persistent jaundice, abdominal distension, and hepatomegaly, with high risk groups being infants and older children. High incidence of metabolic liver diseases in children is due to referrals from smaller hospitals. Early diagnosis, genetic counseling, and non- transplant options are crucial for better treatment.

Keywords : Disease, Chronic, Jaundice, Diagnosis, Treatmnent.

Introduction: Liver diseases significantly impact children's morbidity and mortality, with non-alcoholic fatty liver disease (NAFLD) becoming more prevalent. Geographical heterogeneity in etiology varies, with hepatitis virus being the primary cause in South East Asia. Biliary abnormalities like biliary atresia can manifest as chronic liver disease in children with cirrhosis and portal hypertension. In developing countries, metabolic illnesses causing chronic liver disease have not been thoroughly studied. Methods: Our hospital is a tertiary care facility in a large urban centre and serves as the referral centre. Cases admitted from August 2006 to August 2008 were analyzed and follow up was done. The dates of the onset of illness, fulfillment of diagnostic criteria, diagnosis and treatment all were noted.Conclusion: Chronic liver disease is suspected in children with persistent jaundice, abdominal distension, and hepatomegaly, with high risk groups being infants and older children. High incidence of metabolic liver diseases in children is due to referrals from smaller hospitals. Early diagnosis, genetic counseling, and non- transplant options are crucial for better treatment.

Keywords : Disease, Chronic, Jaundice, Diagnosis, Treatmnent.

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