Authors : Anagh Mukherjee; Swapnanil Sarkar; Priyanka Kumari Sha

Volume/Issue : Volume 11 - 2026, Issue 6 - June

Google Scholar : https://tinyurl.com/npzspyn2

Scribd : https://tinyurl.com/5t9hvt3f

DOI : https://doi.org/10.38124/ijisrt/26jun1491

Note : A published paper may take 4-5 working days from the publication date to appear in PlumX Metrics, Semantic Scholar, and ResearchGate.

Abstract : The primary objective of this investigation was to systematically analyze the phytochemical constituents, structural functional groups, elemental distribution, and in vitro antioxidant and anti-inflammatory activities of the whole plant ethanolic extract of S. pavala. Qualitative phytochemical screening of the ethanolic extract of S. pavala (EESP) indicated a prominent presence of polyphenols, flavonoids, tannins, and terpenoids. FTIR analysis of the organic residues resolved distinctive structural functional groups, notably hydrogen-bonded hydroxyl networks, aliphatic chains and carboxylic/ester carbonyls aromatic skeletal vibration confirming a dense matrix of polar flavonoid glycosides and polyphenols. Quantitative ICP-MS analysis revealed a valuable accumulation of essential minerals, resolved in order of quantitative dominance as Potassium (17365.0±444.0 µg/g), Magnesium (4952.5 ±119.8 µg/g), Calcium (1257.0 ±10.5 µg/g), Sodium (226.5 ±2.0 µg/g), Iron (104.0 ±2.9 µg/g), Manganese (6.0 ±0.5 µg/g), Chromium (15.0 ±0.5 µg/g), Zinc (11.0 ±0.4 µg/g), Molybdenum (0.56 ±0.02 µg/g), Cobalt (0.12±0.01 µg/g) and Selenium (0.09 ±0.01 µg/g). The extract exhibited remarkable, concentration-dependent antioxidant capacity, yielding highly potent IC50 values of 55.40±0.56 µg/mL for DPPH and 50.08 ±0.15 µg/mL for NO scavenging. Furthermore, EESP demonstrated notable anti-inflammatory action by protecting GRBC membranes from thermal lysis with an IC50 of 175.08 ±0.93 µg/mL, and preventing bovine serum albumin denaturation with an IC50 of 188.99±6.16 µg/mL. The compiled evidence demonstrates that the whole plant of S. pavala constitutes a rich reservoir of bio-accessible essential macroelements and trace metals, confirming its therapeutic potential as a natural antioxidant and anti-inflammatory formulation.

Keywords : Strobilanthes pavala; EESP; Cold Maceration; Phytochemical Screening; FTIR; ICP-MS; Anti-inflammatory; Membrane Stabilization; GRBC; Protein Denaturation Assay; Antioxidant; DPPH; SEM.

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