Authors :
Mohammed Aja; Hamidu Ibrahim Musa; David Nadeba Bukbuk
Volume/Issue :
Volume 11 - 2026, Issue 9 - September
Google Scholar :
https://tinyurl.com/527vfavs
DOI :
https://doi.org/10.38124/ijisrt/26sep234
Note : A published paper may take 4-5
working days from the publication date to appear in PlumX Metrics, Semantic Scholar, and
ResearchGate.
Abstract :
Background:
Poliomyelitis, caused by poliovirus, remains a significant public health concern despite global eradication efforts. This
review comprehensively examines the virology, pathogenesis, epidemiology, clinical manifestations, and eradication strategies
for poliovirus infection in children.
Methods:
We conducted a narrative review of peer-reviewed literature, WHO reports, and Global Polio Eradication Initiative (GPEI)
publications.
Keywords :
Poliovirus; Poliomyelitis; Children; Oral Polio Vaccine; Inactivated Polio Vaccine; Eradication; Vaccine-Derived Poliovirus.
References :
- Attardi G, Smith J (1962). Virus-specific protein and a ribonucleic acid associated with ribosomes in poliovirus-infected HeLa cells. Cold Spring Harbor Symposia on Quantitative Biology, 27:271-292.
- Brandenburg B, Lee LY, Lakadamyali M, et al. (2007). Imaging poliovirus entry in live cells. PLOS Biology, 5(7):e183.
- Carter J, Saunders VA (2007). Virology: Principles and Applications. John Wiley & Sons.
- Centers for Disease Control and Prevention (CDC) (2024). Polio immunization guidelines. Available at: https://www.cdc.gov/vaccines/hcp/acip-recs/vacc-specific/polio.html
- De Jesus NH (2007). Epidemics to eradication: the modern history of poliomyelitis. Virology Journal, 4:70.
- Dunnebacke TH, Levinthal JD, Williams RC (1969). Entry and release of poliovirus as observed by electron microscopy of cultured cells. Journal of Virology, 4(4):505-513.
- European Centre for Disease Prevention and Control (ECDC) (2024). Poliomyelitis factsheet. Available at: https://www.ecdc.europa.eu/en/poliomyelitis/facts
- Global Polio Eradication Initiative (GPEI) (2019). Two out of three wild poliovirus strains eradicated. Available at: https://polioeradication.org/news-post/two-out-of-three-wild-poliovirus-strains-eradicated/
- Global Polio Eradication Initiative (GPEI) (2024). History of polio. Available at: https://polioeradication.org/about-polio/history-of-polio/
- Goodsell DS (1998). The Machinery of Life. Copernicus.
- Gómez Yafal A, Kaplan G, Racaniello VR, Hogle JM (1993). Characterization of poliovirus conformational alteration mediated by soluble cell receptors. Virology, 197(1):501-505.
- He Y, Mueller S, Chipman PR, et al. (2003). Complexes of poliovirus serotypes with their common cellular receptor, CD155. Journal of Virology, 77(8):4827-4835.
- Hogle JM, Chow M, Filman DJ (1985). Three-dimensional structure of poliovirus at 2.9 A resolution. Science, 229(4720):1358-1365.
- Jang SK, Kräusslich HG, Nicklin MJ, et al. (1988). A segment of the 5' nontranslated region of encephalomyocarditis virus RNA directs internal entry of ribosomes during in vitro translation. Journal of Virology, 62(8):2636-2643.
- Jiang P, Faase JA, Toyoda H, et al. (2007). Evidence for emergence of diverse polioviruses from C-cluster coxsackie A viruses.
Background:
Poliomyelitis, caused by poliovirus, remains a significant public health concern despite global eradication efforts. This
review comprehensively examines the virology, pathogenesis, epidemiology, clinical manifestations, and eradication strategies
for poliovirus infection in children.
Methods:
We conducted a narrative review of peer-reviewed literature, WHO reports, and Global Polio Eradication Initiative (GPEI)
publications.
Keywords :
Poliovirus; Poliomyelitis; Children; Oral Polio Vaccine; Inactivated Polio Vaccine; Eradication; Vaccine-Derived Poliovirus.