Authors :
Olubunmi Damilola Babatola; Afolabi M. Owojuyigbe; Odunayo Daniel Babatola; Busuyi Kolade Akinola; Olumide Akadiri
Volume/Issue :
Volume 8 - 2023, Issue 11 - November
Google Scholar :
https://tinyurl.com/ydtnz3jn
Scribd :
https://tinyurl.com/46tfzndz
DOI :
https://doi.org/10.5281/zenodo.10437557
Abstract :
The number of Caesarean sections performed
worldwide is increasing as well as the cost of
postoperative treatment. The management of pain post
caesarean section is an important aspect of post-
operative care which has contributed to high cost of
maternal care and may contribute to maternal mortality
especially in resource poor settings. This study assessed
the safety and effectiveness of surgical site infiltration
with lidocaine-epinephrine solution as post caesarean
analgesia compared with non-infiltration. It was a
prospective randomized controlled clinical trial. One
hundred and forty (140) eligible pregnant women
scheduled for elective caesarean section at term in
University of Medical Sciences Teaching Hospital
Complex (UNIMEDTHC) were randomly assigned to the
study and control group, each with 70 participants.
Surgical sites of the study group patients were infiltrated
with 20mls of 2% lidocaine solution (400mg
lidocaine+100μg epinephrine) stat while the control
group patients were not. Both groups received the same
adjuncts analgesic agents whereas rescue analgesics were
given only after complaints of moderate to severe pain.
The rescue analgesic consumption in the first 24 hours
postoperatively was less in the study group compared to
the control (120mg; 480mg). The mean time to onset of
breastfeeding was significantly early (u =3.567, p <
0.001) in the study group compared to the control group.
This study showed that surgical site infiltration with 2%
lidocaine+epinephrine solution following caesarean
section is safe, reduces pain scores and hence use of
rescue analgesics postoperatively, it also increases the
time of onset of breastfeeding thereby decreasing patient
hospital stay.
Keywords :
Caesarean Section, Postoperative Pain, Lidocaine, Epinephrine, Anesthesia.
The number of Caesarean sections performed
worldwide is increasing as well as the cost of
postoperative treatment. The management of pain post
caesarean section is an important aspect of post-
operative care which has contributed to high cost of
maternal care and may contribute to maternal mortality
especially in resource poor settings. This study assessed
the safety and effectiveness of surgical site infiltration
with lidocaine-epinephrine solution as post caesarean
analgesia compared with non-infiltration. It was a
prospective randomized controlled clinical trial. One
hundred and forty (140) eligible pregnant women
scheduled for elective caesarean section at term in
University of Medical Sciences Teaching Hospital
Complex (UNIMEDTHC) were randomly assigned to the
study and control group, each with 70 participants.
Surgical sites of the study group patients were infiltrated
with 20mls of 2% lidocaine solution (400mg
lidocaine+100μg epinephrine) stat while the control
group patients were not. Both groups received the same
adjuncts analgesic agents whereas rescue analgesics were
given only after complaints of moderate to severe pain.
The rescue analgesic consumption in the first 24 hours
postoperatively was less in the study group compared to
the control (120mg; 480mg). The mean time to onset of
breastfeeding was significantly early (u =3.567, p <
0.001) in the study group compared to the control group.
This study showed that surgical site infiltration with 2%
lidocaine+epinephrine solution following caesarean
section is safe, reduces pain scores and hence use of
rescue analgesics postoperatively, it also increases the
time of onset of breastfeeding thereby decreasing patient
hospital stay.
Keywords :
Caesarean Section, Postoperative Pain, Lidocaine, Epinephrine, Anesthesia.
