Authors : Princess Dona C. Bagonggong; Faith S. Mañabo; Ron Arhiz D. Monteclaro; Maureen Kathleen L. Perandos

Volume/Issue : Volume 11 - 2026, Issue 8 - August

Google Scholar : https://tinyurl.com/3bzy5b8y

DOI : https://doi.org/10.38124/ijisrt/26aug777

Note : A published paper may take 4-5 working days from the publication date to appear in PlumX Metrics, Semantic Scholar, and ResearchGate.

Abstract : This study assessed the potential wound-healing effect of ethanolic leaf extract of Sandoricum koetjape (Meliaceae) using an excision wound model in Swiss albino mice. Twenty- four mice were distributed equally into four treatment groups: negative control ointment, positive control ointment, 5% S. koetjape extract ointment, and 10% S. koetjape extract ointment. Wound area was measured on Day 0, Day 3, Day 7, and Day 14, while wound contraction was evaluated on Day 3, Day 7, and Day 14 using Day 0 as the baseline reference. Descriptive statistics, a linear mixed-effects model, day-specific group comparisons, and post hoc tests were used to evaluate visible wound closure and treatment differences. Mean wound area decreased across the observation period in all groups.

Keywords : Sandoricum koetjape, Wound Healing, Excision Wound Model, Ethanolic Extract, Swiss Albino Mice, OECD 402, Phytochemicals, Topical Ointment, Povidone Iodine.

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