Authors :
Kuiate David; Adiele Susan Arrey Eta; Nana Yasmine Laurie; Kougoum Takam Natacha; Fomekong Dieuseul Lothner; Foundikou Vessah Dayib; Apouakone Mefire Aicha; Nanfack Fanny Nadege; Moifo Boniface; Yiagnigni Euloge
Volume/Issue :
Volume 11 - 2026, Issue 1 - January
Google Scholar :
https://tinyurl.com/mt6vzr7d
Scribd :
https://tinyurl.com/3k5teap8
DOI :
https://doi.org/10.38124/ijisrt/26jan947
Note : A published paper may take 4-5 working days from the publication date to appear in PlumX Metrics, Semantic Scholar, and ResearchGate.
Abstract :
Background:
One of the most common cardiovascular conditions impacting people worldwide is coronary artery disease (CAD). It
has been established that this disease is the major cause of death in both developed and developing nations. The CAD
prevalence of lowers patient quality of life and raises mortality and morbidity. There is currently a dearth of information
on the epidemiology of CAD in Cameroon, despite the region's well-established CAD risk factor load. Therefore, the goal of
this research.
Objective:
To assess the prevalence effectiveness and CT presentations of coronary artery disease amongst adults undergoing
coronary artery calcium score at Centre Medical «les Promoteurs de la Bonne Santé Yaoundé».
Materials and method:
This was an analytical cross-sectional study, carried on 80 adult participants undergoing coronary artery calcium
score, which was calculated using the Cochran formula and a convenience sampling method. A structured form was used to
collect data, saved in USB key and later analysed using SPSS version 27.0. This study included participants who gave their
consent. An ethical clearance was obtained and an authorization obtained from the delegation of public health and from the
director of centre medicale les promoteurs de la bonne santé. Participants’ informations were kept private to maintain
confidentiality.
Results:
They were 60 participants. 53.3% were female, 33.3% of participants were aged ≥70yrs. The prevalence of CAD was
80%. Age and sex had a statistically significant relationship (p=0.000). Hypertension and low HDL were the dominant risk
factors accounting for 58.3% respectively. 43.30% of participants were classified as very low risk according FRS. While
46.70% were classified as low risk using CACS. Agreement between the FRS and the CCS was found in 35 patients (58.3%).
Hence there is a statistical significance between FRS and CACS (P value<0.001). Conclusion:
The results of this study confirm the coronary artery calcium score's predictive efficacy and its application as a
coronary artery disease screening tool. Therefore, proper implementation should be done to improve early diagnosis there
by reducing the prevalence of coronary artery disease.
Keywords :
Prevalence, Effectivenesss, CT Presentation, Coronary Artery Disease, Coroscan.
References :
- Malakar, A. Kr., Choudhury, D., Halder, B., Paul, P., Uddin, A., & Chakraborty, S. (2019a). A review on coronary artery disease, its risk factors, and therapeutics. Journal of Cellular Physiology, 234(10), 16812–16823. https://doi.org/10.1002/jcp.28350
- Ralapanawa, U., & Sivakanesan, R. (2021). Epidemiology and the Magnitude of Coronary Artery Disease and Acute Coronary Syndrome: A Narrative Review. Journal of Epidemiology and Global Health, 11(2), 169–177. https://doi.org/10.2991/jegh.k.201217.001.
- Nzina Toupendi, Z., Magny Tiam, E., Temgoua Ngou, M., Boombhi, J., Kingue, S., & Moifo, B. (2024). Relationship between cardiovascular risk factors and coronary artery disease assessed by CAD-RADS. Archives of Cardiovascular Diseases, 117(1, Supplement), S26–S27. https://doi.org/10.1016/j.acvd.2023.10.046
- Ullah, M., Wahab, A., Khan, S. U., Zaman, U., Rehman, K. ur, Hamayun, S., Naeem, M., Ali, H., Riaz, T., Saeed, S., Alsuhaibani, A. M., & Refat, M. S. (2023). Stent as a Novel Technology for Coronary Artery Disease and Their Clinical Manifestation. Current Problems in Cardiology, 48(1), 101415. https://doi.org/10.1016/j.cpcardiol.2022.101415
- Hajar, R. (2017). Risk Factors for Coronary Artery Disease: Historical Perspectives. Heart Views, 18(3), 109. https://doi.org/10.4103/HEARTVIEWS.HEARTVIEWS_106_17
- Osawa, K., Nakanishi, R., & Budoff, M. (2016). Coronary Artery Calcification. Global Heart, 11(3), 287–293. https://doi.org/10.1016/j.gheart.2016.08.001
- Jahangiry, L., Farhangi, M. A., & Rezaei, F. (2017). Framingham risk score for estimation of 10-years of cardiovascular diseases risk in patients with metabolic syndrome. Journal of Health, Population and Nutrition, 36(1), 36. https://doi.org/10.1186/s41043-017-0114-0
- Imoh, L. C., Ani, C. C., Iyua, K. O., Odo, A. I., Amusa, G. A., Osaigbovo, G. O., Isichei, C. O., Agbaji, O. O., Imade, G., Zoakah, A. I., Okeahialam, B. N., & Sagay, A. S. (2020). Subclinical atherosclerosis and associated risk factors among HIV-infected adults in Jos, North Central Nigeria : A cross-sectional study. Pan African Medical Journal, 37(1), Article 1. https://www.ajol.info/index.php/pamj/article/view/232466
- Park, G.-M., Cho, Y.-R., Won, K.-B., Yang, Y. J., Park, S., Ann, S. H., Kim, Y.-G., Park, E. J., Kim, S.-J., Lee, S.-G., Yang, D. H., Kang, J.-W., Lim, T.-H., Kim, H.-K., Choe, J., Lee, S.-W., & Kim, Y.-H. (2020). Triglyceride glucose index is a useful marker for predicting subclinical coronary artery disease in the absence of traditional risk factors. Lipids in Health and Disease, 19(1), 7. https://doi.org/10.1186/s12944-020-1187-0
- Chaikriangkrai, K., Valderrabano, M., Bala, S. K., Alchalabi, S., Graviss, E. A., Nabi, F., Mahmarian, J., & Chang, S. M. (2015). Prevalence and Implications of Subclinical Coronary Artery Disease in Patients With Atrial Fibrillation. The American Journal of Cardiology, 116(8), 1219–1223. https://doi.org/10.1016/j.amjcard.2015.07.041
- Peng, A. W., Mirbolouk, M., Orimoloye, O. A., Osei, A. D., Dardari, Z., Dzaye, O., Budoff, M. J., Shaw, L., Miedema, M. D., Rumberger, J., Berman, D. S., Rozanski, A., Al, -Mallah Mouaz H., Nasir, K., & Blaha, M. J. (2020). Long-Term All-Cause and Cause-Specific Mortality in Asymptomatic Patients With CAC ≥1,000. JACC : Cardiovascular Imaging, 13(1_Part_1), 83–93. https://doi.org/10.1016/j.jcmg.2019.02.005
- Álvarez-Álvarez, M. M., Zanetti, D., Carreras-Torres, R., Moral, P., & Athanasiadis, G. (2017). A survey of sub-Saharan gene flow into the Mediterranean at risk loci for coronary artery disease. European Journal of Human Genetics, 25(4), 472–476. https://doi.org/10.1038/ejhg.2016.200
- Lichtenstein, G., Perlman, A., Shpitzen, S., Durst, R., Shaham, D., Leitersdorf, E., & Szalat, A. (2018). Correlation between coronary artery calcification by non-cardiac CT and Framingham score in young patients. PLOS ONE, 13(3), e0195061. https://doi.org/10.1371/journal.pone.0195061
- Neves, P. O., Andrade, J., & Monção, H. (2017). Coronary artery calcium score: Current status. Radiologia Brasileira, 50, 182–189. https://doi.org/10.1590/0100-3984.2015.0235
Background:
One of the most common cardiovascular conditions impacting people worldwide is coronary artery disease (CAD). It
has been established that this disease is the major cause of death in both developed and developing nations. The CAD
prevalence of lowers patient quality of life and raises mortality and morbidity. There is currently a dearth of information
on the epidemiology of CAD in Cameroon, despite the region's well-established CAD risk factor load. Therefore, the goal of
this research.
Objective:
To assess the prevalence effectiveness and CT presentations of coronary artery disease amongst adults undergoing
coronary artery calcium score at Centre Medical «les Promoteurs de la Bonne Santé Yaoundé».
Materials and method:
This was an analytical cross-sectional study, carried on 80 adult participants undergoing coronary artery calcium
score, which was calculated using the Cochran formula and a convenience sampling method. A structured form was used to
collect data, saved in USB key and later analysed using SPSS version 27.0. This study included participants who gave their
consent. An ethical clearance was obtained and an authorization obtained from the delegation of public health and from the
director of centre medicale les promoteurs de la bonne santé. Participants’ informations were kept private to maintain
confidentiality.
Results:
They were 60 participants. 53.3% were female, 33.3% of participants were aged ≥70yrs. The prevalence of CAD was
80%. Age and sex had a statistically significant relationship (p=0.000). Hypertension and low HDL were the dominant risk
factors accounting for 58.3% respectively. 43.30% of participants were classified as very low risk according FRS. While
46.70% were classified as low risk using CACS. Agreement between the FRS and the CCS was found in 35 patients (58.3%).
Hence there is a statistical significance between FRS and CACS (P value<0.001). Conclusion:
The results of this study confirm the coronary artery calcium score's predictive efficacy and its application as a
coronary artery disease screening tool. Therefore, proper implementation should be done to improve early diagnosis there
by reducing the prevalence of coronary artery disease.
Keywords :
Prevalence, Effectivenesss, CT Presentation, Coronary Artery Disease, Coroscan.