Authors : Doré Levid Mabika; Lexia Malicka Elossi; Thiéry Ndong Mba

Volume/Issue : Volume 11 - 2026, Issue 9 - September

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Google Scholar : https://tinyurl.com/mushv5j9

DOI : https://doi.org/10.38124/ijisrt/26sep1270

Note : A published paper may take 4-5 working days from the publication date to appear in PlumX Metrics, Semantic Scholar, and ResearchGate.

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Abstract : Background: Neonatal jaundice remains a major cause of preventable morbidity in sub-Saharan Africa, yet local epidemiological data in Gabon are scarce.  Objective: To determine the prevalence, assess severity, and identify risk factors associated with neonatal jaundice among newborns admitted to CHUAB in Franceville.  Methods: A 12-month retrospective cross-sectional study was conducted. Medical records of 652 jaundiced newborns were analyzed. Socio-demographic, clinical, and laboratory data were collected, and associations were assessed using multivariate logistic regression.

Keywords : Neonatal Jaundice, Hyperbilirubinemia, G6PDH Deficiency, Risk Factors, Gabon, Neonatal Health.

References :

1. Olusanya, B. O., Vreman, H. J., & Stevenson, D. K. (2018). Neonatal hyperbilirubinaemia in sub-Saharan Africa. The Lancet Global Health, 6(1), e18-e19.
2. Resaz, R., et al. (2025). Acute bilirubin encephalopathy and kernicterus: Pathophysiology and prevention. Journal of Pediatric Neurosciences, 20(1), 12-20.
3. Hamdi, N., et al. (2025). Epidemiology of neonatal jaundice in sub-Saharan Africa: A systematic review. African Journal of Pediatrics, 14(2), 45-58.
4. Mumwi, C., et al. (2025). Neonatal jaundice management in Nairobi: Challenges and outcomes. East African Medical Journal, 102(1), 112-120.
5. World Health Organization. (2024). Guidelines on the identification and management of neonatal jaundice in resource-limited settings. Geneva: World Health Organization.
6. Warsame, S., et al. (2025). Delayed access to phototherapy and neonatal outcomes in East Africa. Pediatrics International, 67(1), 33-41.
7. Bante, A., et al. (2025). Variability in bilirubin monitoring practices in low-resource settings. Journal of Tropical Pediatrics, 71(2), 88-95.
8. American Academy of Pediatrics. (2022). Clinical practice guideline revision: Management of hyperbilirubinemia in the newborn infant 35 or more weeks of gestation. Pediatrics, 150(3), e2022058859.
9. World Health Organization. (2022). Guidelines on the screening and management of G6PD deficiency for malaria elimination and neonatal health. Geneva: World Health Organization.
10. French National Authority for Health (HAS) & UNICEF. (2020). Recommendations for breastfeeding and the management of neonatal jaundice. Paris: HAS..
11. Pediatric Consensus Group. (2021). Consensus statement on the definition and management of early-onset neonatal jaundice. Journal of Perinatology, 41(5), 1023-1030.
12. Eke, C., et al. (2023). Prevalence and risk factors of severe neonatal jaundice in West Africa. Nigerian Journal of Clinical Practice, 26(4), 512-520.
13. Ntadom, G. B., et al. (2023). G6PD deficiency and neonatal hyperbilirubinemia in sub-Saharan Africa: A meta-analysis. Blood Cells, Molecules, and Diseases, 98, 102715.
14. Olusanya, B. O., et al. (2020). Community-based approaches to neonatal jaundice in Africa. Maternal & Child Nutrition, 16(3), e12985.
15. Mbenza, B., et al. (2021). Neonatal jaundice in Kinshasa: Epidemiological profile and management outcomes. Congolese Journal of Medical Sciences, 12(1), 22-30.
16. Adane, S., et al. (2024). Hospital prevalence of neonatal jaundice in Lagos, Nigeria. African Health Sciences, 24(1), 145-153.
17. Bante, A., et al. (2024). Rural-urban disparities in neonatal jaundice care in Senegal. Santé Publique, 36(2), 211-219.
18. Olusanya, B. O., et al. (2023). Improving access to phototherapy in sub-Saharan Africa. Archives of Disease in Childhood - Fetal and Neonatal Edition, 108(2), F112-F118.
19. Ezenwosu, C. U., et al. (2022). Traditional remedies and neonatal jaundice in Nigeria: Risks and delays in care. Journal of Ethnopharmacology, 285, 114876.
20. Kaplan, M., & Hammerman, C. (2022). ABO hemolytic disease of the newborn: Pathophysiology and management. Seminars in Fetal and Neonatal Medicine, 27(1), 101298.
21. Luzzatto, L., et al. (2023). G6PD deficiency: Molecular mechanisms and clinical implications in neonates. Haematologica, 108(3), 612-623.
22. Watchko, J. F., et al. (2023). Bilirubin neurotoxicity in premature infants: Mechanisms and prevention. Pediatric Research, 93(4), 885-894.
23. Hall, M. W., et al. (2025). Immune-mediated hemolysis and early-onset neonatal jaundice. Journal of Pediatrics, 245, 113892.