Authors :
Muhammad Sulaiman Rahama; Abubakar Sani
Volume/Issue :
Volume 5 - 2020, Issue 8 - August
Google Scholar :
http://bitly.ws/9nMw
Scribd :
https://bit.ly/2EIoCLB
DOI :
10.38124/IJISRT20AUG454
Note : A published paper may take 4-5 working days from the publication date to appear in PlumX Metrics, Semantic Scholar, and ResearchGate.
Abstract :
This research work aimed at investigating
some phytochemical constituents present in aloe vera
based antiseptic soap and its activity against some
selected microorganisms. The soap was produced using
hot process and the antimicrobial activity was
performed against Staphylococcus aureus, Escherichia
Coli and Candida albicans using the method of agar
well diffusion. The produced soap exhibited highest
zone of inhibition on Staphylococcus aureus with 8.6
mm, 10.1 mm, 13.8 mm and 15.1 mm at 25 mg/mL, 50
mg/mL, 100 mg/mL and 200 mg/mL respectively, no
inhibition was observed on E. Coli while the C. albicans
was slightly inhibited by the soap by 7.6 mm, 9.0 mm,
13.2 mm at 50 mg/mL, 100 mg/mL, 200mg/mL
respectively. The phytochemical screening conducted
confirmed the presence of tannins, saponins, reducing
sugar and flavonoid in the plant extract. The results of
the investigations clearly indicated that aloe vera based
soap had possessed antimicrobial activity against the
tested microorganisms due to the presence of the
confirmned phytoconstituents. Likewise pH,
formability, and antimicrobial activity of the produced
soap were comparable with the commercial soap.
Keywords :
Phytochemical Screening, Antiseptic Soap, Microorganisms, Agar Well Diffusion, Antimicrobial Activity
This research work aimed at investigating
some phytochemical constituents present in aloe vera
based antiseptic soap and its activity against some
selected microorganisms. The soap was produced using
hot process and the antimicrobial activity was
performed against Staphylococcus aureus, Escherichia
Coli and Candida albicans using the method of agar
well diffusion. The produced soap exhibited highest
zone of inhibition on Staphylococcus aureus with 8.6
mm, 10.1 mm, 13.8 mm and 15.1 mm at 25 mg/mL, 50
mg/mL, 100 mg/mL and 200 mg/mL respectively, no
inhibition was observed on E. Coli while the C. albicans
was slightly inhibited by the soap by 7.6 mm, 9.0 mm,
13.2 mm at 50 mg/mL, 100 mg/mL, 200mg/mL
respectively. The phytochemical screening conducted
confirmed the presence of tannins, saponins, reducing
sugar and flavonoid in the plant extract. The results of
the investigations clearly indicated that aloe vera based
soap had possessed antimicrobial activity against the
tested microorganisms due to the presence of the
confirmned phytoconstituents. Likewise pH,
formability, and antimicrobial activity of the produced
soap were comparable with the commercial soap.
Keywords :
Phytochemical Screening, Antiseptic Soap, Microorganisms, Agar Well Diffusion, Antimicrobial Activity
