Authors :
Dr. Sivagna Duddumpudi; Dr. Nazaf Nazir Parol; Dr. Sachin Padman; Dr. Venugopal Reddy I
Volume/Issue :
Volume 9 - 2024, Issue 3 - March
Google Scholar :
https://tinyurl.com/5s6bw6kk
Scribd :
https://tinyurl.com/mr34895b
DOI :
https://doi.org/10.38124/ijisrt/IJISRT24MAR1560
Abstract :
Background:
One of the most frequent neurological emergencies
in pediatrics, central nervous system infections cause a
considerable amount of death and morbidity. Especially
in newborns, the symptoms are frequently modest,
therefore a strong index of suspicion is needed to make
the diagnosis. Inadequate or delayed treatment may
result in fatalities or other severe consequences.
Objective:
To ascertain the frequency, clinical characteristics,
and etiological makeup of kids hospitalized in tertiary
PICU due to acute encephalitis syndrome.
Results of kids referred to tertiary PICUs with acute
encephalitis symptoms.
Study Design:
Hospital based prospective study.
Participants:
Children with AES from one month up to 18 years
of age admitted in PICU of hospitals.
Intervention:
Thorough clinical assessments were completed, and
blood samples will be sent for various baseline
biochemical analyses. In every instance, samples of blood
and urine were sent for sensitivity and culture while
adhering to strict aseptic protocol. In every incidence of
fever with altered sensorium, neuroimaging and CSF
analysis will be carried out.The history, clinical
examination, and pertinent laboratory investigations are
used to determine the etiology of AES.
Results:
Out of the one hundred cases that were examined,
five had J.E., thirty had rickettsia, twenty had dengue,
one had varicella, twelve had COVID-19, five had
measles, four were pyogenic, one had tuberculosis, twelve
had ADEM, and nine were undiagnosed. A total of 45
patients were lost to follow-up throughout the follow-up
period. Of the patients, 16 had hearing loss, 10 had speech
loss, 15 had extra pyramidal abnormality, 21 had
behavioral abnormality, and 21 had cranial nerve
impairments.
Conclusion:
AES is a persistent public health issue that requires
immediate attention, as well as cooperation and support
from other sectors. Strengthening primary health care is
urgently needed to provide access to both routine and
emergency care, both of which are essential for better
results.
Keywords :
Acute Encephalitis Syndrome; Cerebrospinal Fluid Analysis; Clinical Profile; Glasgow Outcome Score.
Background:
One of the most frequent neurological emergencies
in pediatrics, central nervous system infections cause a
considerable amount of death and morbidity. Especially
in newborns, the symptoms are frequently modest,
therefore a strong index of suspicion is needed to make
the diagnosis. Inadequate or delayed treatment may
result in fatalities or other severe consequences.
Objective:
To ascertain the frequency, clinical characteristics,
and etiological makeup of kids hospitalized in tertiary
PICU due to acute encephalitis syndrome.
Results of kids referred to tertiary PICUs with acute
encephalitis symptoms.
Study Design:
Hospital based prospective study.
Participants:
Children with AES from one month up to 18 years
of age admitted in PICU of hospitals.
Intervention:
Thorough clinical assessments were completed, and
blood samples will be sent for various baseline
biochemical analyses. In every instance, samples of blood
and urine were sent for sensitivity and culture while
adhering to strict aseptic protocol. In every incidence of
fever with altered sensorium, neuroimaging and CSF
analysis will be carried out.The history, clinical
examination, and pertinent laboratory investigations are
used to determine the etiology of AES.
Results:
Out of the one hundred cases that were examined,
five had J.E., thirty had rickettsia, twenty had dengue,
one had varicella, twelve had COVID-19, five had
measles, four were pyogenic, one had tuberculosis, twelve
had ADEM, and nine were undiagnosed. A total of 45
patients were lost to follow-up throughout the follow-up
period. Of the patients, 16 had hearing loss, 10 had speech
loss, 15 had extra pyramidal abnormality, 21 had
behavioral abnormality, and 21 had cranial nerve
impairments.
Conclusion:
AES is a persistent public health issue that requires
immediate attention, as well as cooperation and support
from other sectors. Strengthening primary health care is
urgently needed to provide access to both routine and
emergency care, both of which are essential for better
results.
Keywords :
Acute Encephalitis Syndrome; Cerebrospinal Fluid Analysis; Clinical Profile; Glasgow Outcome Score.
