Authors :
Samuel Filima; Victor Benoit
Volume/Issue :
Volume 11 - 2026, Issue 8 - August
Google Scholar :
https://tinyurl.com/ycxbveyc
DOI :
https://doi.org/10.38124/ijisrt/26aug1599
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working days from the publication date to appear in PlumX Metrics, Semantic Scholar, and
ResearchGate.
Abstract :
Background:
Androgenetic alopecia (AGA) is the primary driver of progressive pattern hair loss and is characterized by androgenmediated follicular miniaturization. Non-surgical stabilization of hair density relies on established pharmacological agents
with documented long-term evidence.
Objectives:
To evaluate the 6-to-12-month change in hair density, gender-stratified response, adverse-event incidence, and
treatment adherence in patients receiving a combined finasteride and minoxidil protocol.
Methods:
A single-arm, prospective, longitudinal observational cohort of n = 443 patients receiving combination therapy was
followed over 12 months. Hair density per cm² was measured by standardized digital phototrichogram analysis at baseline
(T₀), 6 months (T₁), and 12 months (T₂). Group comparisons are descriptive; no inferential statistics were performed.
References :
- Kaufman KD, Olsen EA, Whiting D, et al. Finasteride in the treatment of men with androgenetic alopecia. J Am Acad Dermatol. 1998;39(4):578-589.
- Olsen EA, Dunlap FE, Funicella T, et al. A randomized clinical trial of 5% topical minoxidil versus 2% topical minoxidil and placebo in the treatment of androgenetic alopecia in men. J Am Acad Dermatol. 2002;47(3):377-385.
- Suchonwanit P, Thammarucha S, Leerunyakul K. Minoxidil and its use in hair disorders: a review. Drug Des Devel Ther. 2019;13:2777-2786.
- Adil A, Godwin M. The effectiveness of treatments for androgenetic alopecia: a systematic review and meta-analysis. J Am Acad Dermatol. 2017;77(1):136-141.e5.
- Chen L, Zhang J, Wang L, Wang H, Chen B. The efficacy and safety of finasteride combined with topical minoxidil for androgenetic alopecia: a systematic review and meta-analysis. Aesthetic Plast Surg. 2020;44(3):962-970.
- Vera Clinic Academy. Clinical Efficacy of Regenerative Hair Therapies and Combined Hair Transplantation Outcomes: A 12-Month Prospective Observational Cohort. Unpublished data / manuscript in preparation.
Background:
Androgenetic alopecia (AGA) is the primary driver of progressive pattern hair loss and is characterized by androgenmediated follicular miniaturization. Non-surgical stabilization of hair density relies on established pharmacological agents
with documented long-term evidence.
Objectives:
To evaluate the 6-to-12-month change in hair density, gender-stratified response, adverse-event incidence, and
treatment adherence in patients receiving a combined finasteride and minoxidil protocol.
Methods:
A single-arm, prospective, longitudinal observational cohort of n = 443 patients receiving combination therapy was
followed over 12 months. Hair density per cm² was measured by standardized digital phototrichogram analysis at baseline
(T₀), 6 months (T₁), and 12 months (T₂). Group comparisons are descriptive; no inferential statistics were performed.
