Ramifications of Vitamin B12 Deficiency and its Beneficial Effects

Authors : Anurag; Soumyadip Mukherjee; Jeetendra Kumar Gupta; Kuldeep Singh; Shivendra Kumar; Karan Kumar; Shiv Prakash Rajput; Indra Pal Singh; Mohit Saxena; Pankaj Rajput; Meenakshi

Volume/Issue : Volume 8 - 2023, Issue 1 - January

Google Scholar : https://bit.ly/3IIfn9N

Scribd : https://bit.ly/3kcnGnP

DOI : https://doi.org/10.5281/zenodo.7527794

Vitamin B12 (methylcobalamin) deficiency can lead to a variety of health problems, including anaemia, fatigue, weakness, and memory loss. If left untreated, it can also lead to more serious problems such as nerve damage and problems with vision, hearing, and balance. Methylcobalamin, an active form of vitamin B12, aids in producing S-adenosylmethionine and methionine. It is necessary for the synthesis of DNA, the appropriate creation of red blood cells, the integrity of myelin, and brain function. Worldwide, the most common form of vitamin B12 insufficiency is observed among vegetarians, and its equivalent, methylcobalamin, may help. The majority of common illnesses, including cardiovascular disorders, diabetes, anaemia, Hyperhomocysteinemia, and degenerative conditions, may benefit from this medication. Methylcobalamin enhances correct neuron function, which lessens the symptoms of Alzheimer's disease, Parkinsonism, dementia, and neuropathic syndromes. It also aids in the production of neuronal lipids and the regeneration of axonal nerves. Peripheral neuropathy may be treated with it. Also, taking methylcobalamin supplements has been shown to ease the symptoms of Parkinson's disease, speed up remyelination in diseases that damage the nerves (which is why this compound is used in experiments), and help the body make more red blood cells.

Keywords : Methylcobalamin, Neuropathy, Methionine, Deficiency, Homocysteine.


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