Authors :
Ashutosh Mishra; Harekrishna Majhi
Volume/Issue :
Volume 10 - 2025, Issue 11 - November
Google Scholar :
https://tinyurl.com/ymx492ch
Scribd :
https://tinyurl.com/2nwhru2m
DOI :
https://doi.org/10.38124/ijisrt/25nov313
Note : A published paper may take 4-5 working days from the publication date to appear in PlumX Metrics, Semantic Scholar, and ResearchGate.
Note : Google Scholar may take 30 to 40 days to display the article.
Abstract :
Low-grade appendiceal mucinous neoplasms (LAMNs) are rare epithelial tumors of the appendix that can lead
to pseudomyxoma peritonei (PMP) if mucin spills into the peritoneal cavity. We report a 65-year-old man who presented
with right iliac fossa pain and an appendicular mass. Exploratory laparotomy revealed a dilated appendix with mucinous
content and ~200 mL of acellular mucin. Histopathology confirmed a well-differentiated LAMN (Grade 1) with acellular
mucin reaching the serosa (pT4a), no invasion, and negative margins. Postoperative recovery was uneventful, and follow-
up PET-CT revealed no recurrence. Appendectomy with lavage and surveillance was deemed sufficient. Surgeons should
consider LAMN in appendicular masses associated with mucinous collections.
Keywords :
LAMN, Acellular Mucin, Pseudomyxoma Peritonei, Appendectomy, Appendiceal Neoplasm, HIPEC.
References :
- Carr NJ, et al. A consensus for classification and pathologic reporting of pseudomyxoma peritonei. Am J Surg Pathol. 2016;40(1):14-26.
- Shaib WL, Assi R, Shamseddine A, et al. Low-grade appendiceal mucinous neoplasms: A case series. J Surg Case Rep. 2025;214.
- Guner M, Aydin C. Low-grade appendiceal mucinous neoplasm: What is the best treatment? Cureus. 2023;15:e46591.
- Fournier KF, Rafeeq S. Low-grade appendiceal mucinous neoplasm of uncertain malignant potential. Ann Surg Oncol. 2016;24:187-193.
- Glasgow SC, Gaertner W. ASCRS clinical practice guidelines for appendiceal neoplasms. Dis Colon Rectum. 2019;62:1425-1438.
- Ballentine SJ, Carr J, Bekhor EY. Updated staging and patient outcomes in low-grade appendiceal mucinous neoplasms. Mod Pathol. 2021;34:104-115.
Low-grade appendiceal mucinous neoplasms (LAMNs) are rare epithelial tumors of the appendix that can lead
to pseudomyxoma peritonei (PMP) if mucin spills into the peritoneal cavity. We report a 65-year-old man who presented
with right iliac fossa pain and an appendicular mass. Exploratory laparotomy revealed a dilated appendix with mucinous
content and ~200 mL of acellular mucin. Histopathology confirmed a well-differentiated LAMN (Grade 1) with acellular
mucin reaching the serosa (pT4a), no invasion, and negative margins. Postoperative recovery was uneventful, and follow-
up PET-CT revealed no recurrence. Appendectomy with lavage and surveillance was deemed sufficient. Surgeons should
consider LAMN in appendicular masses associated with mucinous collections.
Keywords :
LAMN, Acellular Mucin, Pseudomyxoma Peritonei, Appendectomy, Appendiceal Neoplasm, HIPEC.