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Authors :- Alaa Bader Eldein Abdalla Gasim, Wafa Ibrahim Elhag

Volume/Issue:  Volume 3 Issue 1

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Objectives:Blood group antigens were associated with gastritis, which is potentially caused by Helicobacter pylori. It was recently demonstrated that the receptor for H.pylori is the blood group antigen Lewis, which is exposed only in blood group O This study aimed to detect possible correlation between H.pylori Infection and ABO blood groups in patients with gastritis signs and symptoms. Methods:This was descriptive cross-sectional, study which carried out between July and October 2017 in which 90 patients suffering from gastritis symptoms attending to AL Amal Gabal Awlia Hospital were enrolled, blood specimen were collected blood group phenotype and Rhesus were determined by tube method. Ninety patient’s sera underwent tested by ELISA for H.pylori (IgG-IgM) after examined for H.pylori by screening test (ICT). Ethical Clearance was obtained from Research Ethical Board-AL Neelain university data was collected using questionnaire and analyzed by SPSS. Results:Out of the Total Ninety patients with gastritis sign and symptom’s, 27(30%) were males and 63(70%) were females their age ranged 14-69 year’s, with mean(38.7).The total patients were positive for H.pylori 78 (86.6%), while 12 (13.3%) patient’s negative. regarding gender female had high seropositivity (65.3%) . out of Total 66 positive of IgG and 12 both IgM ,IgG positive. and 12 both IgG ,IgM negative, regarding blood grouping, most of study population were group O with frequency 38(77.5%) ,14 (73.6%) blood group B, 11(16.6%) Blood group A and 3(4.5%) Blood group AB. This implies that there was statistically significant correlation between the O blood group, positive and H.pylori infection in gastritis disease patient. P.Value=0.023 and 0.038 respectively. Conclusion: This study revealed statistical a significant association between blood group O and H. pylori infection.