Liver diseases are associated with adrenal
insufficiency, predominantly in critically ill patients. In
our first of kind study, we measured renal resistive index
and predicted adrenal insufficiency as measured by
serum cortisol level in decompensated cirrhosis patients.
Methodology: A prospective observational cohort study
done from October 2014 to June 2016 included 100
decompensated cirrhosis patients admitted in Lady
Hardinge Medical college, New Delhi. ACTH stimulation
test was done with 250mcg/dl, basal cortisol, and cortisol
after 60 mins of stimulation was recorded. Renal
resistive index was calculated in all patients and charted
in excel sheet for statistical analysis.
Results: 28% patient were found to have adrenal
insufficiency. On univariate analysis, INR, serum total
bilirubin, serum creatinine, low HDL, CTP score, MELD
score, plasma renin activity level, renal resistive index
correlated with patients of adrenal insufficiency.
Multivariate analysis showed in patients with adrenal
insufficiency, MELD score had odds ratio
Keywords : Cirrhosis, Adrenal insufficiency, ACTH, Renal resistive index, Portal hypertension