Background : Mixed infection is a challenge to the treating clinician. Vial hepatitis and leptospirosis co-infection has not been frequently referred to in medical literature as both present as acute febrile illness with jaundice and may reveal non-specific laboratory findings. Hepatitis A infection and leptospirosis are prevalent in developing countries Objective: This retrospective study is aimed at determining the presence of hepatitis and leptospirosis co-infection among patients of acute febrile illness with jaundice. Methods: Retrospective data of IgM ELISA for leptospirosis, anti-HAV antibodies and anti-HEV antibodies ELISA was retrieved for analysis. Serum samples of patients of acute febrile illness with jaundice were collected and processed. A total of 92 serum samples were received over a period of one year from April 2022 to March 2023 for IgM ELISA for leptospirosis, anti-HAV antibodies and anti-HEV antibodies ELISA.

Keywords : HAV, HEV, ELISA, AST, ALT, MOF, ARDS.