Authors :
Dr. Jyoti Mehta; Dr. Kirthi Koushik ; Dr. Ram Alva
Volume/Issue :
Volume 6 - 2021, Issue 1 - January
Google Scholar :
http://bitly.ws/9nMw
Scribd :
https://bit.ly/3ejlW6n
Abstract :
Adrenocortical carcinoma (ACC) is a rare and
highly aggressive disease with higher rate of recurrence
and poor survival. The main treatment is primary
surgical resection with or without mitotane therapy. The
role of radiation therapy is still controversial.
Radiotherapy has limited role due to the risk of normal
tissue toxicity, as the proximity of the adrenals to
radiosensitive structures, like kidney, stomach, intestine,
and spinal cord. However, newer techniques have made
radiotherapy (RT) safe and effective for use in the
management of adrenal carcinoma. Adjuvant radiation
has shown a recurrence free survival by 18%. We
hereby presenting the case series of 3 patients treated
with adjuvant radiation that had good long term
outcome
Adrenocortical carcinoma (ACC) is a rare and
highly aggressive disease with higher rate of recurrence
and poor survival. The main treatment is primary
surgical resection with or without mitotane therapy. The
role of radiation therapy is still controversial.
Radiotherapy has limited role due to the risk of normal
tissue toxicity, as the proximity of the adrenals to
radiosensitive structures, like kidney, stomach, intestine,
and spinal cord. However, newer techniques have made
radiotherapy (RT) safe and effective for use in the
management of adrenal carcinoma. Adjuvant radiation
has shown a recurrence free survival by 18%. We
hereby presenting the case series of 3 patients treated
with adjuvant radiation that had good long term
outcome