Authors :
Smita Swami, Sanjay Swami, Dr. V. W Patil, Dr. L. Abhichandani
Volume/Issue :
Volume 4 - 2019, Issue 8 - August
Google Scholar :
https://goo.gl/DF9R4u
Scribd :
https://bit.ly/2HjTO2l
Abstract :
Diabetes is a condition that impairs the body's
ability to process blood glucose. Type 2 diabetes has
several causes- genetics and lifestyle are the most
important ones. A combination of these factors
can cause insulin resistance, when your body doesn't use
insulin as well as it should. Insulin resistance is the most
common cause of type 2 diabetes. Alcohol abuse is said to
influence several changes in the cytokine levels. The
present study was undertaken to evaluate the role of
cytokines, which seems to be the probable cause of insulin
resistance leading to type 2 diabetes. 400 subjects were
included in the study divided into Control (Group I) 100
non-alcoholic control, 100 alcoholic healthy controls.
Diabetic subjects as Group II- 100 newly diagnosed non-
alcoholic diabetic patients and 100 newly diagnosed
alcoholic diabetic patients respectively, both from the age
group of 35-55 years. The result specified that there is a
strong relation between increased cytokines levels due to
alcohol abuse, insulin resistance and diabetic progression
and its complication.
Keywords :
Diabetes Mellitus, Interleukins, Cytokines, Alcohol, IL1, IL-6, IL-8, IL-10
Diabetes is a condition that impairs the body's
ability to process blood glucose. Type 2 diabetes has
several causes- genetics and lifestyle are the most
important ones. A combination of these factors
can cause insulin resistance, when your body doesn't use
insulin as well as it should. Insulin resistance is the most
common cause of type 2 diabetes. Alcohol abuse is said to
influence several changes in the cytokine levels. The
present study was undertaken to evaluate the role of
cytokines, which seems to be the probable cause of insulin
resistance leading to type 2 diabetes. 400 subjects were
included in the study divided into Control (Group I) 100
non-alcoholic control, 100 alcoholic healthy controls.
Diabetic subjects as Group II- 100 newly diagnosed non-
alcoholic diabetic patients and 100 newly diagnosed
alcoholic diabetic patients respectively, both from the age
group of 35-55 years. The result specified that there is a
strong relation between increased cytokines levels due to
alcohol abuse, insulin resistance and diabetic progression
and its complication.
Keywords :
Diabetes Mellitus, Interleukins, Cytokines, Alcohol, IL1, IL-6, IL-8, IL-10
