⚠ Official Notice: www.ijisrt.com is the official website of the International Journal of Innovative Science and Research Technology (IJISRT) Journal for research paper submission and publication. Please beware of fake or duplicate websites using the IJISRT name.



Role of Physiotherapy in the Management of Non-Cardiac Chest Pain: A Narrative Review


Authors : Dr. Pooja Gurudasani; Dr. Ashlesha Mankar; Dr. Sachin Tendulkar; Dr. Amit Jaiswal; Dr. Aastha Patel; Dr. Sudesh Waydande; Dr. Priyanka Ghumnani

Volume/Issue : Volume 11 - 2026, Issue 9 - September


Google Scholar : https://tinyurl.com/4jmfphud

DOI : https://doi.org/10.38124/ijisrt/26sep1378

Note : A published paper may take 4-5 working days from the publication date to appear in PlumX Metrics, Semantic Scholar, and ResearchGate.


Abstract : Background: Non-cardiac chest pain (NCCP) is a heterogeneous clinical presentation in which chest pain persists despite the absence of an identified cardiac cause after appropriate medical evaluation. The underlying contributors may be musculoskeletal, vascular, neurological, respiratory, gastrointestinal, psychological, or a combination of these mechanisms.  Objective: To synthesize the available evidence regarding physiotherapy and rehabilitation approaches used for NCCP and NCCP-like presentations across musculoskeletal, vascular, neurological, respiratory, and gastrointestinal/psychological contributors.  Methods: A narrative review was developed from the supplied NCCP evidence set comprising 18 articles published between 1993 and 2026. The evidence included randomized controlled trials, prospective studies, case reports, systematic reviews, a systematic review and meta-analysis, narrative reviews, and a trial protocol. Findings were organized thematically according to the major clinical contributors to NCCP.  Results: Musculoskeletal studies reported benefits from selected manual therapy, heat, stretching, trigger-point-oriented interventions, and functional restoration, although long-term comparative superiority over self-management was inconsistent. Thoracic outlet syndrome literature supported postural correction, stretching, scapular stabilization, neural mobilization, exercise, taping, and technology-assisted rehabilitation, although protocols were heterogeneous. Cervical angina literature emphasized recognition of cervical pathology and conservative management, but direct physiotherapy trials were limited. Respiratory rehabilitation, including aerobic and inspiratory muscle training, showed promising findings in NCCP accompanied by dyspnea. Diaphragmatic breathing, relaxation, and dynamic neuromuscular stabilization were also investigated in gastrointestinal and psychological NCCP.  Conclusion: The reviewed evidence supports a mechanism-oriented, individualized, and multidisciplinary approach to NCCP rather than a universal physiotherapy protocol. Better diagnostic phenotyping, standardized intervention reporting, adequately powered trials, clinically relevant outcomes, and longer follow-up are needed to strengthen the evidence base.

Keywords : Non-Cardiac Chest Pain; Physiotherapy; Physical Therapy; Musculoskeletal Chest Pain; Thoracic Outlet Syndrome; Cervical Angina; Respiratory Rehabilitation; Diaphragmatic Breathing; Rehabilitation.

References :

  1. Japa JP, Zitser P, Ehioghae M, Yoon K, Lee L, Thiru S, et al. Cervical Angina: An Often-Overlooked Cause of Noncardiac Chest Pain. JBJS Rev. 2026;14(2). doi:10.2106/JBJS.RVW.25.00238.
  2. Burgstaller JM, Jenni BF, Steurer J, Held U, Wertli MM. Treatment efficacy for non-cardiovascular chest pain: a systematic review and meta-analysis. PLoS One. 2014;9(8):e104722.
  3. Fass R, Achem SR. Noncardiac chest pain: epidemiology, natural course and pathogenesis. J Neurogastroenterol Motil. 2011;17(2):110-123. doi:10.5056/jnm.2011.17.2.110.
  4. Katz PO, Dunbar KB, Schnoll-Sussman FH, Greer KB, Yadlapati R, Spechler SJ. ACG clinical guideline for the diagnosis and management of gastroesophageal reflux disease. Am J Gastroenterol. 2022;117(1):27-56. doi:10.14309/ajg.0000000000001538.
  5. Jensen S. Musculoskeletal causes of chest pain. Aust Fam Physician. 2001;30(9):834-839.
  6. Stochkendahl MJ, Christensen HW, Vach W, Høilund-Carlsen PF, Haghfelt T, Hartvigsen J. Diagnosis and treatment of musculoskeletal chest pain: design of a multi-purpose trial. BMC Musculoskelet Disord. 2008;9:40.
  7. Huzmeli I, Yildiz Ozer A. Effectiveness of a training program for a patient with non-cardiac chest pain that combines intervention to improve quality of life, psychological state, and functional capacity: a case report. Biopsychosoc Med. 2023;17:27.
  8. Suryavanshi AR, Venkatesan P, Shetty R, Pawar M. Effect of Diaphragmatic Breathing Exercise, Jacobson's Relaxation Technique and Dynamic Neuromuscular Stabilization on Gastrointestinal and Psychological Causes of Noncardiac Chest Pain: A Randomized Controlled Trial. Pain Res Manag. 2025;2025:8124858.
  9. Berg AT, Stafne S, Hiller A, Slørdahl S, Aamot IL. Physical therapy intervention in patients with non-cardiac chest pain following a recent cardiac event: a randomized controlled trial. SAGE Open Med. 2015;3:2050312115580799.
  10. Stochkendahl MJ, Christensen HW, Vach W, Høilund-Carlsen PF, Haghfelt T, Hartvigsen J. A randomized clinical trial of chiropractic treatment and self-management in patients with acute musculoskeletal chest pain: 1-year follow-up. J Manipulative Physiol Ther. 2012;35(4):254-262.
  11. Collins E, Orpin M. Physical Therapy Management of Neurogenic Thoracic Outlet Syndrome. Thorac Surg Clin. 2021;31(1):61-69.
  12. Kenny RA, Traynor GB, Withington D, Keegan DJ. Thoracic outlet syndrome: a useful exercise treatment option. Am J Surg. 1993;165(2):282-284.
  13. Şengül M, Şengül ST. Efficacy of trigger point injection therapy in noncardiac chest pain: a randomized controlled trial. Turk J Phys Med Rehabil. 2024;70(1):98-104.
  14. Goharinejad S, Ahrari MN, Moulaei K, Sarafinejad A. Evaluating the effects of mobile application-based rehabilitation on improving disability and pain in patients with disputed thoracic outlet syndrome: a randomized controlled trial. Int J Med Inform. 2024;185:105400.
  15. Newman DP, Jansen BJ, Scozzafava A, Smith R, Mclean BC. Rib Mediated Non-Cardiac Chest Pain: A Case Report. Cureus. 2020 Oct 6;12(10):e10831. doi: 10.7759/cureus.10831. PMID: 33173637; PMCID: PMC7645301.
  16. Jones MR, Prabhakar A, Viswanath O, et al. Thoracic Outlet Syndrome: A Comprehensive Review of Pathophysiology, Diagnosis, and Treatment. Pain Ther. 2019;8:5-18. doi:10.1007/s40122-019-0124-2.
  17. Joshi AV, Shinde S, Chaudhary NS, Chaudhary S. Evidence-Based Diagnostic and Therapeutic Methods for Thoracic Outlet Syndrome: A Systematic Review. Cureus. 2026;18(5):e108241.
  18. Ortaç EA, Sarpel T, Benlidayı İÇ. Effects of Kinesio Taping on pain, paresthesia, functional status, and overall health status in patients with symptomatic thoracic outlet syndrome. Acta Orthop Traumatol Turc. 2020;54(4):394-401.
  19. Elshinnawy AM, Eraky ZS, Abdallah EA, Elmasry HM, El-Samouly HM. Effect of osteopathic technique on respiratory parameters and pain in thoracic outlet syndrome. J Bodyw Mov Ther. 2026;46:262-266.
  20. Feng F, Chen X, Shen H. Cervical Angina: A Literature Review on Its Diagnosis, Mechanism, and Management. Asian Spine J. 2021;15(4):550-556.
  21. Wells P. Cervical angina. Am Fam Physician. 1997;55(6):2262-2264.

Background: Non-cardiac chest pain (NCCP) is a heterogeneous clinical presentation in which chest pain persists despite the absence of an identified cardiac cause after appropriate medical evaluation. The underlying contributors may be musculoskeletal, vascular, neurological, respiratory, gastrointestinal, psychological, or a combination of these mechanisms.  Objective: To synthesize the available evidence regarding physiotherapy and rehabilitation approaches used for NCCP and NCCP-like presentations across musculoskeletal, vascular, neurological, respiratory, and gastrointestinal/psychological contributors.  Methods: A narrative review was developed from the supplied NCCP evidence set comprising 18 articles published between 1993 and 2026. The evidence included randomized controlled trials, prospective studies, case reports, systematic reviews, a systematic review and meta-analysis, narrative reviews, and a trial protocol. Findings were organized thematically according to the major clinical contributors to NCCP.  Results: Musculoskeletal studies reported benefits from selected manual therapy, heat, stretching, trigger-point-oriented interventions, and functional restoration, although long-term comparative superiority over self-management was inconsistent. Thoracic outlet syndrome literature supported postural correction, stretching, scapular stabilization, neural mobilization, exercise, taping, and technology-assisted rehabilitation, although protocols were heterogeneous. Cervical angina literature emphasized recognition of cervical pathology and conservative management, but direct physiotherapy trials were limited. Respiratory rehabilitation, including aerobic and inspiratory muscle training, showed promising findings in NCCP accompanied by dyspnea. Diaphragmatic breathing, relaxation, and dynamic neuromuscular stabilization were also investigated in gastrointestinal and psychological NCCP.  Conclusion: The reviewed evidence supports a mechanism-oriented, individualized, and multidisciplinary approach to NCCP rather than a universal physiotherapy protocol. Better diagnostic phenotyping, standardized intervention reporting, adequately powered trials, clinically relevant outcomes, and longer follow-up are needed to strengthen the evidence base.

Keywords : Non-Cardiac Chest Pain; Physiotherapy; Physical Therapy; Musculoskeletal Chest Pain; Thoracic Outlet Syndrome; Cervical Angina; Respiratory Rehabilitation; Diaphragmatic Breathing; Rehabilitation.

Paper Submission Last Date
31 - October - 2026

SUBMIT YOUR PAPER CALL FOR PAPERS
Video Explanation for Published paper

Never miss an update from Papermashup

Get notified about the latest tutorials and downloads.

Subscribe by Email

Get alerts directly into your inbox after each post and stay updated.
Subscribe
OR

Subscribe by RSS

Add our RSS to your feedreader to get regular updates from us.
Subscribe