The self-experimental procedures performed
by doctors on their own, before (or instead of) extending
the investigation to their patients is a very well known
and ethical practice for the progress of medical
diagnosis and therapies.
In the Doctor-Care-Yourself Network (born in
University of Modena medical school, Italy), this issue is
formally part of the duties of participants.
Our paper describes a self-experiment on
intravenous perfusion of biliary salts in healthy doctors
to verify the safety of different dosages, before trying
them on the patients. The inventor of the parenteral
treatment preliminary submitted himself only at first, to
verify the feasibility and possible untoward effect of the
Subsequently, after this first positive selfexperience, other three colleagues spontaneously joined
the same protocol, which was confirmed to be absolutely
safe and optimally tolerated.