Authors :
Chandrakala. S.A; Lakshminrusimhan. D.K.S; Paramasivam preethi; Sowmya. R; Sivagurunathan. N
Volume/Issue :
Volume 9 - 2024, Issue 6 - June
Google Scholar :
https://tinyurl.com/3hvpv8x3
Scribd :
https://tinyurl.com/hwmpk7d3
DOI :
https://doi.org/10.38124/ijisrt/IJISRT24JUN1344
Note : A published paper may take 4-5 working days from the publication date to appear in PlumX Metrics, Semantic Scholar, and ResearchGate.
Abstract :
Salivary diagnostics, an emerging field in
medical research, leverages the analysis of saliva for non-
invasive detection, monitoring, and management of
various diseases. This abstract explores the potential of
saliva as a diagnostic fluid, highlighting its advantages
such as ease of collection, cost-effectiveness, and patient
acceptability compared to traditional blood or tissue
sampling. Key biomarkers identified in saliva include
proteins, nucleic acids, and metabolites that reflect
systemic health conditions, oral diseases, infectious
agents, and even systemic diseases like cancer and
diabetes. Advances in technology, such as biosensors and
genomic analysis, enhance the sensitivity and specificity
of salivary diagnostics, paving the way for personalized
medicine and early intervention strategies. Challenges
including standardization, variability in saliva
composition, and regulatory approval are also discussed,
underscoring the need for further research and clinical
validation. Salivary diagnostics holds promise as a
valuable tool in future healthcare, potentially
transforming how diseases are diagnosed and managed
globally.
Keywords :
Saliva, Biomarkers, Oral and Systemic Diseases.
References :
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- Janice M. Yoshizawa,a, Christopher A. Schafer,a, Jason J. Schafer,b, James J. Farrell,c, Bruce J. Paster,d,e, and David T. W. Salivary Biomarkers: Toward Future Clinical and Diagnostic Utilities. Clin Microbiol Rev. 2013 Oct; 26(4): 781–791.
Salivary diagnostics, an emerging field in
medical research, leverages the analysis of saliva for non-
invasive detection, monitoring, and management of
various diseases. This abstract explores the potential of
saliva as a diagnostic fluid, highlighting its advantages
such as ease of collection, cost-effectiveness, and patient
acceptability compared to traditional blood or tissue
sampling. Key biomarkers identified in saliva include
proteins, nucleic acids, and metabolites that reflect
systemic health conditions, oral diseases, infectious
agents, and even systemic diseases like cancer and
diabetes. Advances in technology, such as biosensors and
genomic analysis, enhance the sensitivity and specificity
of salivary diagnostics, paving the way for personalized
medicine and early intervention strategies. Challenges
including standardization, variability in saliva
composition, and regulatory approval are also discussed,
underscoring the need for further research and clinical
validation. Salivary diagnostics holds promise as a
valuable tool in future healthcare, potentially
transforming how diseases are diagnosed and managed
globally.
Keywords :
Saliva, Biomarkers, Oral and Systemic Diseases.