Authors : Dr. Sunil Nirmale; Dr. Rahul Kshirsagar; Dr. Sadashiv Daokar; Dr. Nikita Sarate; Dr. Sana Khan; Dr. Madhuri Khatod; Dr. Manasi Pachpande

Volume/Issue : Volume 11 - 2026, Issue 1 - January

Google Scholar : https://tinyurl.com/mry3exv4

Scribd : https://tinyurl.com/46maedd6

DOI : https://doi.org/10.38124/ijisrt/26jan1220

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Abstract : Aim: The present in vitro investigation was designed to comparatively assess the dentinal tubule occluding ability of three commercially available desensitizing dentifrices containing Novamin, nano-hydroxyapatite, and propolis.  Materials and Methods: Forty extracted human premolars and molars were utilized to prepare standardized dentin discs from the mid-coronal region. To simulate dentinal hypersensitivity, the specimens were treated with 37% phosphoric acid for 30 seconds to remove the smear layer and open the dentinal tubules. The samples were randomly allocated into four groups (n = 10): Group I— control (saline), Group II—Novamin-based dentifrice, Group III—nano-hydroxyapatite-based dentifrice, and Group IV— propolis-based dentifrice. The dentifrices were applied once daily for two minutes over a period of seven days. Following treatment, the extent of dentinal tubule occlusion was evaluated using scanning electron microscopy (SEM).  Results: Specimens treated with the nano-hydroxyapatite dentifrice demonstrated the highest degree of dentinal tubule occlusion, followed by the Novamin-containing dentifrice. The propolis-based dentifrice showed partial tubule occlusion, while the control group exhibited predominantly patent tubules.  Conclusion: All tested desensitizing dentifrices were capable of occluding dentinal tubules to varying extents. Among them, nano-hydroxyapatite was found to be the most effective. Propolis-containing dentifrice, owing to its natural origin and moderate efficacy, may be considered a viable alternative for the management of dentinal hypersensitivity.

Keywords : Dentinal Hypersensitivity, Dentinal Tubule Occlusion, Novamin, Nano-Hydroxyapatite, Propolis, Scanning Electron Microscopy.

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