The debates between science and religion have been a long way discussion in many life aspects; especially how one is compared to another and seen as more superior or inferior. Science has dramatically developed since the Renaissance era in the 14th century to the Age of Reason in the late 18th century, until today. The tremendous science advancement has been portrayed well in Mary Shelley’s book entitled Frankenstein where the scientific act of revival is clearly shown and practised. This study wants to emphasise the science mythology in the novel, related to how science and religion are depicted both in the novel and social practice. Using Roland Barthes’ semiotic approach, this research has analysed how science and religion should be perceived through denotative, connotative, and myth interpretations. Finally, it can be concluded that there is a tangible bond between science and religion that is supposed to create harmony for both aspects of social practices.

Keywords : Act of Revival, Age of Reason, Frankenstein, , Religion, Science Mythology.