Authors :
Debajit Dewan; Suman Pattanayak; Lakshmi Kanta Kanthal; Souranava Jana; Anulipi Biswas; Sandipan Bag; Debkumar Sahoo; Sudip Pal; Bibartan Bhattachrya
Volume/Issue :
Volume 7 - 2022, Issue 11 - November
Google Scholar :
https://bit.ly/3IIfn9N
Scribd :
https://bit.ly/3gwVAC3
DOI :
https://doi.org/10.5281/zenodo.7349495
Abstract :
- The plant Vernonia cinerea of the family
Asteraceae is widely distributed in the most tropical
and subtropical part of the India. It is commonly known
as ‘Sahadevi’. According to Ayurvedic pharmacopoeia
of India it is recommended for the intermittent fever,
blisters, pain, diuresis, various gastro-intestinal
disorder, boils, malaria, vaginal discharge and in case of
psychoneurosis. Therefore, the present study was
designed to evaluate the antimicrobial activity as well as
to describe the presence of phytoconstituents through
phytochemical screening of the hydro-alcoholic extract
of the whole parts of the plant. We carried out the
phytochemical screening of the Vernonia cinerea which
shows the presence of carbohydrate, reducing and nonreducing sugar, glycoside, phytosterol & terpenoids,
phenolic compound & tannin, flavonoids. Antimicrobial
activity of the Vernonia cinerea against most
dominating microbes like Staphylococcus aureus,
Escherichia coli, Proteus mirabilis, Candida Spp.
(albicans) through well diffusion method. The hydroalcoholic extract at various concentrations produces
significant antimicrobial and antifungal activity against
the selected microorganism when compared with
standard drug Norfloxacin for antibacterial and
antifungal activity.
Keywords :
Vernonia cinerea, Hydro-alcoholic extract, Phytochemical screening, Anti-microbial activity.
- The plant Vernonia cinerea of the family
Asteraceae is widely distributed in the most tropical
and subtropical part of the India. It is commonly known
as ‘Sahadevi’. According to Ayurvedic pharmacopoeia
of India it is recommended for the intermittent fever,
blisters, pain, diuresis, various gastro-intestinal
disorder, boils, malaria, vaginal discharge and in case of
psychoneurosis. Therefore, the present study was
designed to evaluate the antimicrobial activity as well as
to describe the presence of phytoconstituents through
phytochemical screening of the hydro-alcoholic extract
of the whole parts of the plant. We carried out the
phytochemical screening of the Vernonia cinerea which
shows the presence of carbohydrate, reducing and nonreducing sugar, glycoside, phytosterol & terpenoids,
phenolic compound & tannin, flavonoids. Antimicrobial
activity of the Vernonia cinerea against most
dominating microbes like Staphylococcus aureus,
Escherichia coli, Proteus mirabilis, Candida Spp.
(albicans) through well diffusion method. The hydroalcoholic extract at various concentrations produces
significant antimicrobial and antifungal activity against
the selected microorganism when compared with
standard drug Norfloxacin for antibacterial and
antifungal activity.
Keywords :
Vernonia cinerea, Hydro-alcoholic extract, Phytochemical screening, Anti-microbial activity.