Authors :
Sakariye Abdullahi Hassan-Tuuryare; Suleyman Abdullahi Mohamed; Timothy Kimutai
Volume/Issue :
Volume 9 - 2024, Issue 6 - June
Google Scholar :
https://tinyurl.com/2adjtukn
Scribd :
https://tinyurl.com/bdhjwj3t
DOI :
https://doi.org/10.38124/ijisrt/IJISRT24JUN1232
Note : A published paper may take 4-5 working days from the publication date to appear in PlumX Metrics, Semantic Scholar, and ResearchGate.
Abstract :
Introduction:
Brucellosis is a disease that can be contracted by
humans through contact with infected animals or animal
products. It can be transmitted through contaminated
dairy products, so caution must be exercised when
handling and preparing food. By taking precautions, the
spread of this disease can be mitigated to protect both
humans and animals. (1) Brucella spp is a type of bacteria
that can cause an infection. The symptoms of this
infection can range from mild flu-like symptoms to severe
complications that affect different parts of the body.
Because Brucella is able to invade the body and avoid the
immune system, it's important to get an accurate
diagnosis and start treatment as soon as possible. (2). (3)
Method:
The study was conducted at Kalkaal Hospital from
2019 to 2023, spanning three years. Patients who went to
the hospital's Outpatient department and were screened
for Brucella were included in the study. Data on patients'
demographics, including their residence, gender, age, and
Brucella screening results, were collected and recorded
over the study period. The participants' blood samples
were gathered and analyzed for Brucella infection
through a variety of diagnostic The clinical assessment
included an examination of symptoms, medical history,
and possible exposure to Brucella. To detect specific
antibodies (IgM and IgG) against Brucella present in the
blood serum, serological tests such as the Serum
Agglutination Test (SAT), ELISA, and Rose Bengal Test
were conducted. The blood samples were analyzed to
identify the Brucella bacteria through blood cultures. In
addition, the presence of Brucella DNA was confirmed in
various clinical samples using Polymerase Chain Reaction
(PCR). The Kalkaal Hospital Research Review Board
gave approval for the study protocol. Data cleaning was
carried out with the help of Excel. The analysis of data
was performed using SPSS software version 25.
Results:
According to the analysis of the data, 30.3% of
patients were men, and 69.7% of patients were women.
The age ranges were 0–19: 1245 (8.1%), 20–29: 3951
(25.7%), 30-39: 3027 (19.7%), 40–49: 1786 (11.6%), and
50+: 4582. (29.9 percent). In addition, 14884 (97.0%) of
the outcomes were negative, while only 465 (3.0%) were
positive.
Conclusion:
The research carried out at Kalkaal Hospital in
Mogadishu, Somalia, has revealed important information
about the prevalence of Brucella infection in the area. The
results suggest that a significant number of patients have
tested positive for Brucella antibodies, which indicates
that the disease is a significant burden on the local
population. These findings add to the global knowledge of
brucellosis and emphasize its severe and long-term
effects. It is important for experts in this field to have
further discussions and come to a consensus on how to
address this issue.
References :
- Arenas-Gamboa AM, Rossetti CA, Chaki SP, Garcia-Gonzalez DG, Adams LG, Ficht TA. Human Brucellosis and Adverse Pregnancy Outcomes. Curr Trop Med Rep. 2016 Dec;3(4):164–72.
- Xavier MN, Costa ÉA, Paixão TA, Santos RL. The genus Brucella and clinical manifestations of brucellosis. Cienc Rural. 2009 Aug 21;39(7):2252–60.
- Dean AS, Crump L, Greter H, Hattendorf J, Schelling E, Zinsstag J. Clinical Manifestations of Human Brucellosis: A Systematic Review and Meta-Analysis. Carabin H, editor. PLoS Negl Trop Dis. 2012 Dec 6;6(12):e1929.
- Tuon FF, Gondolfo RB, Cerchiari N. Human-to-human transmission of Brucella - a systematic review. Trop Med Int Health. 2017 May;22(5):539–46.
- Mesner O, Riesenberg K, Biliar N, Borstein E, Bouhnik L, Peled N, et al. The Many Faces of Human-to-Human Transmission of Brucellosis: Congenital Infection and Outbreak of Nosocomial Disease Related to an Unrecognized Clinical Case. Clinical Infectious Diseases. 2007 Dec 15;45(12):e135–40.
- Meltzer E, Sidi Y, Smolen G, Banai M, Bardenstein S, Schwartz E. Sexually Transmitted Brucellosis in Humans. CLIN INFECT DIS. 2010 Jul 15;51(2):e12–5.
- Vigeant P, Mendelson J, Miller MA. Human to Human Transmission of Brucella Melitensis. Canadian Journal of Infectious Diseases. 1995;6(3):153–5.
- Mableson HE, Okello A, Picozzi K, Welburn SC. Neglected Zoonotic Diseases—The Long and Winding Road to Advocacy. PLOS Neglected Tropical Diseases. 2014 Jun 5;8(6):e2800.
- Kiambi SG, Fèvre EM, Omolo J, Oundo J, de Glanville WA. Risk factors for acute human brucellosis in Ijara, north-eastern Kenya. Zinsstag J, editor. PLoS Negl Trop Dis. 2020 Apr 1;14(4):e0008108.
- Njeru J, Wareth G, Melzer F, Henning K, Pletz MW, Heller R, et al. A systematic review of brucellosis in Kenya: disease frequency in humans and animals and risk factors for human infection. BMC Public Health. 2016 Aug 22;16(1):853.
- Yagupsky P, Morata P, Colmenero JD. Laboratory Diagnosis of Human Brucellosis. Clin Microbiol Rev. 2019 Dec 18;33(1):e00073-19.
- Aloufi AD, Memish ZA, Assiri AM, McNabb SJN. Trends of reported human cases of brucellosis, Kingdom of Saudi Arabia, 2004–2012. JEGH. 2015;6(1):11.
- Zeinalian Dastjerdi M, Fadaei Nobari R, Ramazanpour J. Epidemiological features of human brucellosis in central Iran, 2006–2011. Public Health. 2012 Dec;126(12):1058–62.
Introduction:
Brucellosis is a disease that can be contracted by
humans through contact with infected animals or animal
products. It can be transmitted through contaminated
dairy products, so caution must be exercised when
handling and preparing food. By taking precautions, the
spread of this disease can be mitigated to protect both
humans and animals. (1) Brucella spp is a type of bacteria
that can cause an infection. The symptoms of this
infection can range from mild flu-like symptoms to severe
complications that affect different parts of the body.
Because Brucella is able to invade the body and avoid the
immune system, it's important to get an accurate
diagnosis and start treatment as soon as possible. (2). (3)
Method:
The study was conducted at Kalkaal Hospital from
2019 to 2023, spanning three years. Patients who went to
the hospital's Outpatient department and were screened
for Brucella were included in the study. Data on patients'
demographics, including their residence, gender, age, and
Brucella screening results, were collected and recorded
over the study period. The participants' blood samples
were gathered and analyzed for Brucella infection
through a variety of diagnostic The clinical assessment
included an examination of symptoms, medical history,
and possible exposure to Brucella. To detect specific
antibodies (IgM and IgG) against Brucella present in the
blood serum, serological tests such as the Serum
Agglutination Test (SAT), ELISA, and Rose Bengal Test
were conducted. The blood samples were analyzed to
identify the Brucella bacteria through blood cultures. In
addition, the presence of Brucella DNA was confirmed in
various clinical samples using Polymerase Chain Reaction
(PCR). The Kalkaal Hospital Research Review Board
gave approval for the study protocol. Data cleaning was
carried out with the help of Excel. The analysis of data
was performed using SPSS software version 25.
Results:
According to the analysis of the data, 30.3% of
patients were men, and 69.7% of patients were women.
The age ranges were 0–19: 1245 (8.1%), 20–29: 3951
(25.7%), 30-39: 3027 (19.7%), 40–49: 1786 (11.6%), and
50+: 4582. (29.9 percent). In addition, 14884 (97.0%) of
the outcomes were negative, while only 465 (3.0%) were
positive.
Conclusion:
The research carried out at Kalkaal Hospital in
Mogadishu, Somalia, has revealed important information
about the prevalence of Brucella infection in the area. The
results suggest that a significant number of patients have
tested positive for Brucella antibodies, which indicates
that the disease is a significant burden on the local
population. These findings add to the global knowledge of
brucellosis and emphasize its severe and long-term
effects. It is important for experts in this field to have
further discussions and come to a consensus on how to
address this issue.