Shelf Life Determination of Vitamin C in Aqueous Solutions: Effect of Vitamin C Concentration and Addition of Antioxidants


Authors : AhmadRahaf; Al haushey Lama

Volume/Issue : Volume 9 - 2024, Issue 1 - January

Google Scholar : http://tinyurl.com/5hc62aej

Scribd : http://tinyurl.com/yc7mvp89

DOI : https://doi.org/10.5281/zenodo.10853091

Abstract : Ascorbic acid or Vitamin C (Vit C) is sensitive to oxidation process therefore, its formulation should take its sensibility into consideration for assuring maximum stability.The objective of this work was to stabilize (Vit C) in aqueous solutions by modifying the concentration of Vit C and by the addition of different antioxidant: metabisulfite Na (MBS), hydroquinone (HQ) and vitamin E (Vit E). Kinetic of Vit C degradation was estimated by determining reaction order, rate constants and by calculating shelf lives (t90). The results showed that shelf life of Vit C was enhanced when a higher concentration of Vit C was used (15 days vs. ≈10 days at low concentration). Use of MBS and HQ (both at concentrations: 0.25 and 0.5%) increased Vit C shelf life (≈21, 29 days for MBS and 18, 20 days for HQ). However, lower shelf lives were reported when Vit E (at two concentrations 0.25 and 0.5%) was used.

Keywords : Vitamin, Shelf Life, Stability, Antioxidant.

Ascorbic acid or Vitamin C (Vit C) is sensitive to oxidation process therefore, its formulation should take its sensibility into consideration for assuring maximum stability.The objective of this work was to stabilize (Vit C) in aqueous solutions by modifying the concentration of Vit C and by the addition of different antioxidant: metabisulfite Na (MBS), hydroquinone (HQ) and vitamin E (Vit E). Kinetic of Vit C degradation was estimated by determining reaction order, rate constants and by calculating shelf lives (t90). The results showed that shelf life of Vit C was enhanced when a higher concentration of Vit C was used (15 days vs. ≈10 days at low concentration). Use of MBS and HQ (both at concentrations: 0.25 and 0.5%) increased Vit C shelf life (≈21, 29 days for MBS and 18, 20 days for HQ). However, lower shelf lives were reported when Vit E (at two concentrations 0.25 and 0.5%) was used.

Keywords : Vitamin, Shelf Life, Stability, Antioxidant.

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