Authors : Sana Siddiqua; Salma Tabassum

Volume/Issue : Volume 9 - 2024, Issue 5 - May

Google Scholar : https://tinyurl.com/9fea37w3

Scribd : https://tinyurl.com/ah5w2jf8

DOI : https://doi.org/10.38124/ijisrt/IJISRT24MAY928

Abstract : Spindle neoplasm an uncommon variant of benign lipomatous tumor, occurs mostly in the posterior neck or the shoulder  It contains well circumscribed & no aggressive subcutaneous mass  Spindle cell neoplasm may be traced to epithelial, mesenchymal & odontogenic  Latin (AE1/AE3, K1), K1, K18, and EMA appear to be the most sensitive/reliable epithelial spindle cell neoplasms.  Spindle cell neoplasms can be benign or malignant. Under a microscope, the neoplasm is composed of adipocytes flat cells and long, thin spindle cells. In a spindle cell lipoma, the adipocytes are surrounded by spindle cells.  The diagnosis test includes immunohistochemistry and fluorescence in site hybridization (FISH) to confirm the diagnosis and to include other tumors that can look like a spindle cell lipoma. If a spindle cell neoplasm is large or uncomfortable, it can be removed.

References :

1. https://my.clevelandclinic.org/health/diseases/25020-spindle-cell-sarcoma
2. https://pubmed.ncbi.nlm.nih.gov/27686175/
3. https://emedicine.medscape.com/article/1057855-overview#a
4. https://www.metropolisindia.com/blog/tag/lipoma-symptoms
5. https://qwarkhealth.com/conditions/spindle-cell-lipoma/
6. hhttps://www.dermatologyadvisor.com/home/decision-support-in-medicine/dermatology/spindle-cell-
   lipoma/#:~:text=Systemic%20Implications%20and%20Complications,
   the%20pedunculated%20mass%20was%20aspirated.
7. https://www.slideshare.net/jideososaajayi/lipomas-48484675
8. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5376837/
9. https://journaljpri.com/index.php/JPRI/article/view/6623
10. https://en.wikivet.net/Spindle_Cell_Tumours#:~:
    text=Generally%20spindle%20cell%20tumours%20do
    ,may%20fade%20into%20the%20background.
11. https://www.baptisthealth.com/care-services/
    conditions-treatments/spindle-cell-sarcoma
12. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10359697/#:~:
    text=Typically%2C%20spindle%20cell%20lipomas%20are,
    breast%2C%20perineum%20and%20oral%20cavity.
13. https://www.slideshare.net/madhusudhanreddy107/spindle-cell-lesions-part-i
14. https://www.mayoclinic.org/diseases-conditions/lipoma/symptoms-causes/syc-20374470
15. Le Nail L.R., Crenn V., Rosset P., Ropars M. Management of adipose tumors in the limbs. Orthop Traumatol Surg Res. 2022;108(Suppl 1) [PubMed] [Google Scholar]

16. Khashper A., Zheng J., Nahal A., Discepola F. Imaging characteristics of spindle cell lipoma and its variants. Skeletal Radiol. 2014;43(5):591–597. [PubMed] [Google Scholar]
17. E.H. Courtiss, M.B. Donelan  Skin sensation after suction lipectomy: A prospective study of 50 consecutive patients Plast Reconstr Surg, 81 (4) (1988), pp. 550-553 View at publisher CrossRefView in ScopusGoogle Scholar
18. C.A. French, T. Mentzel, H. Kutzner, C.D.M. Fletcher Intradermal spindle cell/pleomorphic lipoma: A distinct subsetAm J Dermatopathol, 22 (6) (2000), pp. 496-502 View in ScopusGoogle Scholar
19. J.A. Machol, J.G. Cusic, E.A. O'Connor, J.R. Sanger, H.S Matloub Spindle cell lipoma of the neck: Review of the literature and case report Plast Reconstr Surg Glob Open, 3 (11) (2015), p. e55View in ScopusGoogle Scholar
20. M. Nilbert, et al. Characterization of the 12q13-15 amplicon in soft tissue tumors Cancer Genet. Cytogenet., 83 (1) (1995), pp. 32-310.1016/s0165-4608(95)00016-x View PDFView articleView in ScopusGoogle Scholar
21. Shuai Chen, et al. Spindle cell lipoma: clinicopathologic characterization of 40 cases Int. J. Clin. Exp. Pathol., 12 (2019) 7 2613-2621. 1 Jul Google Scholar