Authors :
Dr. Bhaskar Shenoy; Dr. Suvarna.B; Dr. Venugopal Reddy.I; Kumudavalli.N
Volume/Issue :
Volume 8 - 2023, Issue 5 - May
Google Scholar :
https://bit.ly/3TmGbDi
Scribd :
https://t.ly/9d8rj
DOI :
https://doi.org/10.5281/zenodo.8001753
Abstract :
Thrombocytosis, or elevations of platelet
count in the peripheral blood to values >400,000/mm3, is
common in infancy and childhood, occurring in 3-13%
of children. Primary thrombocytosis is divided into
familial & essential thrombocytosis, while reactive
thrombocytosis occurs frequently. Most of the available
studies on the thrombocytosis in children are from
developed countries, and there appears to be
geographical variations in causes of reactive
thrombocytosis (RT). The present study was undertaken
to ascertain common etiology of reactive thrombocytosis,
to assist the general pediatrician in dealing with this
common hematological finding in everyday clinical
practice. This study was conducted on 100 inpatients
admitted under the department of pediatrics, Manipal
hospital, Bangalore from August 2011 to July 2012.
Consecutive children of both sexes up to the age of 5
years, having thrombocytosis (platelet count >
4,00,000/mm3) were enrolled. An appropriate EDTA
blood sample was collected at admission and platelet
counts were analysed by automated analyser (Beckman
coulter 780) and reconfirmed by manual method.
Relevant investigations were done according to the
clinical history and physical findings, to establish the
diagnosis. Age, sex and varied diagnosis were correlated
with the thrombocytosis and results were analysed.
Reactive thrombocytosis is a very common observed
condition in children, unlike primary thrombocytosis
which is rare. Most of the literature is from the western
world, and this study was conducted to know the
common etiologies responsible for reactive
thrombocytosis in this part of the country. In most
children with reactive thrombocytosis, platelet counts
are modestly elevated up to 700,
Keywords :
Thrombocytosis, Platelet Count, Hematology, Children, Blood Sample
Thrombocytosis, or elevations of platelet
count in the peripheral blood to values >400,000/mm3, is
common in infancy and childhood, occurring in 3-13%
of children. Primary thrombocytosis is divided into
familial & essential thrombocytosis, while reactive
thrombocytosis occurs frequently. Most of the available
studies on the thrombocytosis in children are from
developed countries, and there appears to be
geographical variations in causes of reactive
thrombocytosis (RT). The present study was undertaken
to ascertain common etiology of reactive thrombocytosis,
to assist the general pediatrician in dealing with this
common hematological finding in everyday clinical
practice. This study was conducted on 100 inpatients
admitted under the department of pediatrics, Manipal
hospital, Bangalore from August 2011 to July 2012.
Consecutive children of both sexes up to the age of 5
years, having thrombocytosis (platelet count >
4,00,000/mm3) were enrolled. An appropriate EDTA
blood sample was collected at admission and platelet
counts were analysed by automated analyser (Beckman
coulter 780) and reconfirmed by manual method.
Relevant investigations were done according to the
clinical history and physical findings, to establish the
diagnosis. Age, sex and varied diagnosis were correlated
with the thrombocytosis and results were analysed.
Reactive thrombocytosis is a very common observed
condition in children, unlike primary thrombocytosis
which is rare. Most of the literature is from the western
world, and this study was conducted to know the
common etiologies responsible for reactive
thrombocytosis in this part of the country. In most
children with reactive thrombocytosis, platelet counts
are modestly elevated up to 700,
Keywords :
Thrombocytosis, Platelet Count, Hematology, Children, Blood Sample
