Sulfasalazine: Adverse Effects and Literature Review - Case Report


Authors : Christian Camilo Lasso Maldonado; Dalyla Leal Vargas

Volume/Issue : Volume 8 - 2023, Issue 7 - July

Google Scholar : https://bit.ly/3TmGbDi

Scribd : https://tinyurl.com/yckar6ub

DOI : https://doi.org/10.5281/zenodo.8241131

Abstract : DRESS (Drug Reaction with Eosinophilia and Systemic Symptoms) is a very rare and potentially fatal drug-induced delayed hypersensitivity syndrome. We present the case of a 60-year-old woman who had been on sulfasalazine for 2 months to treat rheumatoid arthritis. She was admitted for 4 days presenting a pruriginous maculopapular erythema predominantly on the trunk and fever of 39.5 °C. Blood tests showed marked eosinophilia (800/mm3), a cholestatic pattern, and severe inflammation. Sulfasalazine-induced DRESS syndrome was diagnosed.

Keywords : “DRESS Syndrome”, “Sulfasalazine Induced DRESS Syndrome”, “Sulfasalazine Adverse Effects”, “Sulfasalazine”

DRESS (Drug Reaction with Eosinophilia and Systemic Symptoms) is a very rare and potentially fatal drug-induced delayed hypersensitivity syndrome. We present the case of a 60-year-old woman who had been on sulfasalazine for 2 months to treat rheumatoid arthritis. She was admitted for 4 days presenting a pruriginous maculopapular erythema predominantly on the trunk and fever of 39.5 °C. Blood tests showed marked eosinophilia (800/mm3), a cholestatic pattern, and severe inflammation. Sulfasalazine-induced DRESS syndrome was diagnosed.

Keywords : “DRESS Syndrome”, “Sulfasalazine Induced DRESS Syndrome”, “Sulfasalazine Adverse Effects”, “Sulfasalazine”

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