DRESS (Drug Reaction with Eosinophilia and
Systemic Symptoms) is a very rare and potentially fatal
drug-induced delayed hypersensitivity syndrome. We
present the case of a 60-year-old woman who had been on
sulfasalazine for 2 months to treat rheumatoid arthritis.
She was admitted for 4 days presenting a pruriginous
maculopapular erythema predominantly on the trunk and
fever of 39.5 °C. Blood tests showed marked eosinophilia
(800/mm3), a cholestatic pattern, and severe inflammation.
Sulfasalazine-induced DRESS syndrome was diagnosed.
Keywords : “DRESS Syndrome”, “Sulfasalazine Induced DRESS Syndrome”, “Sulfasalazine Adverse Effects”, “Sulfasalazine”